Enhancement of the effects of intermittent parathyroid hormone (1-34) by bone morphogenetic protein in a rat femoral open fracture model

Enhancement of the effects of intermittent parathyroid hormone (1-34) by bone morphogenetic protein in a rat femoral open fracture model

Abstract Background Nonunion in cases of open fracture is common. Both bone morphogenetic protein 2 (BMP-2) and parathyroid hormone (PTH) have been used to enhance bone healing. We investigated the combination of BMP-2 and PTH and examined the effects on a rat model of open femoral fractures. Method...

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Bibliographic Details
Main Authors: Shozo Kanezaki, Masashi Miyazaki, Toshinobu Ishihara, Naoki Notani, Tetsutaro Abe, Yuhta Tsubouchi, Masashi Kataoka, Hiroshi Tsumura
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Parathyroid hormone
Teriparatide
Bone morphogenetic protein
Open fracture, Femur
Online Access:https://doi.org/10.1186/s13018-019-1470-9

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