Human Cytomegalovirus Infection in Women of Childbearing Age Throughout Fars Province - Iran: A Population-based Cohort Study
Human cytomegalovirus (hCMV) has been described as an important etiological agent of intrauterine infection in women of childbearing age that causes congenital malformation. In the present study we examined 844 serum samples from women of child-bearing age for the presence of IgM and IgG antibodies...
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| Format: | Article |
| Language: | English |
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Malaysian Society for Microbiology
2007-01-01
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| Series: | Malaysian Journal of Microbiology |
| Subjects: | |
| Online Access: | http://web.usm.my/mjm/issues/vol3no2/research5.pdf |
| _version_ | 1818932678705020928 |
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| author | Arabpour, M. Kaviyanee, K. Jankhah, A. Yaghobi, R. |
| author_facet | Arabpour, M. Kaviyanee, K. Jankhah, A. Yaghobi, R. |
| author_sort | Arabpour, M. |
| collection | DOAJ |
| description | Human cytomegalovirus (hCMV) has been described as an important etiological agent of intrauterine infection in women of childbearing age that causes congenital malformation. In the present study we examined 844 serum samples from women of child-bearing age for the presence of IgM and IgG antibodies against hCMV by Elisa technique. 764 out of 844 (93%) of the cases were seropositive for hCMV-IgG and 45 (5.4%) cases were seropositive for hCMV-IgM. An increase in the rate of IgG seroprevalance was associated with an increase in age and parity. The IgG seroprevalance rate was inversely proportional to increasing abortions. Intrestingly seasonal variation affected IgG seroprevalance. There was an increasing trend in IgM positivity rate with age in women less than 29 years. hCMV seroprevalence rate was higher in women from rural as compared to those of urban areas. Finally hCMV primary infections occured in 2.4 % of all pregnancis and it is estimated that up to 0.3% of all congenital disorders, through out Fars province, were due to hCMV. We suggest a role of child to mother hCMV transmission and sexual maturity as the most probable epidemiological factors of hCMV seroprevalence among women of child bearing age. |
| first_indexed | 2024-12-20T04:36:18Z |
| format | Article |
| id | doaj.art-4e3f6af48af4476596d353e0f4178f7b |
| institution | Directory Open Access Journal |
| issn | 1823-8262 2231-7538 |
| language | English |
| last_indexed | 2024-12-20T04:36:18Z |
| publishDate | 2007-01-01 |
| publisher | Malaysian Society for Microbiology |
| record_format | Article |
| series | Malaysian Journal of Microbiology |
| spelling | doaj.art-4e3f6af48af4476596d353e0f4178f7b2022-12-21T19:53:14ZengMalaysian Society for MicrobiologyMalaysian Journal of Microbiology1823-82622231-75382007-01-01322328Human Cytomegalovirus Infection in Women of Childbearing Age Throughout Fars Province - Iran: A Population-based Cohort StudyArabpour, M.Kaviyanee, K.Jankhah, A.Yaghobi, R.Human cytomegalovirus (hCMV) has been described as an important etiological agent of intrauterine infection in women of childbearing age that causes congenital malformation. In the present study we examined 844 serum samples from women of child-bearing age for the presence of IgM and IgG antibodies against hCMV by Elisa technique. 764 out of 844 (93%) of the cases were seropositive for hCMV-IgG and 45 (5.4%) cases were seropositive for hCMV-IgM. An increase in the rate of IgG seroprevalance was associated with an increase in age and parity. The IgG seroprevalance rate was inversely proportional to increasing abortions. Intrestingly seasonal variation affected IgG seroprevalance. There was an increasing trend in IgM positivity rate with age in women less than 29 years. hCMV seroprevalence rate was higher in women from rural as compared to those of urban areas. Finally hCMV primary infections occured in 2.4 % of all pregnancis and it is estimated that up to 0.3% of all congenital disorders, through out Fars province, were due to hCMV. We suggest a role of child to mother hCMV transmission and sexual maturity as the most probable epidemiological factors of hCMV seroprevalence among women of child bearing age.http://web.usm.my/mjm/issues/vol3no2/research5.pdfHuman CytomegalovirusSeroprevalenceIgM and IgG antibodies |
| spellingShingle | Arabpour, M. Kaviyanee, K. Jankhah, A. Yaghobi, R. Human Cytomegalovirus Infection in Women of Childbearing Age Throughout Fars Province - Iran: A Population-based Cohort Study Malaysian Journal of Microbiology Human Cytomegalovirus Seroprevalence IgM and IgG antibodies |
| title | Human Cytomegalovirus Infection in Women of Childbearing Age Throughout Fars Province - Iran: A Population-based Cohort Study |
| title_full | Human Cytomegalovirus Infection in Women of Childbearing Age Throughout Fars Province - Iran: A Population-based Cohort Study |
| title_fullStr | Human Cytomegalovirus Infection in Women of Childbearing Age Throughout Fars Province - Iran: A Population-based Cohort Study |
| title_full_unstemmed | Human Cytomegalovirus Infection in Women of Childbearing Age Throughout Fars Province - Iran: A Population-based Cohort Study |
| title_short | Human Cytomegalovirus Infection in Women of Childbearing Age Throughout Fars Province - Iran: A Population-based Cohort Study |
| title_sort | human cytomegalovirus infection in women of childbearing age throughout fars province iran a population based cohort study |
| topic | Human Cytomegalovirus Seroprevalence IgM and IgG antibodies |
| url | http://web.usm.my/mjm/issues/vol3no2/research5.pdf |
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