Parameter identifiability and redundancy in a general class of stochastic carcinogenesis models.
BACKGROUND: Heidenreich et al. (Risk Anal 1997 17 391-399) considered parameter identifiability in the context of the two-mutation cancer model and demonstrated that combinations of all but two of the model parameters are identifiable. We consider the problem of identifiability in the recently devel...
Main Authors: | Mark P Little, Wolfgang F Heidenreich, Guangquan Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2797326?pdf=render |
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