Clinical and laboratory diagnosis of dengue fever in travelers

The paper presents the analysis of clinical and laboratory symptoms in 35 adult patients with denger fever, Novosibirsk residents, which travelled in endemic countries, mostly Tailand. The classic form of the disease was determined in all cases. The moderate form was in 71,5% patients, the severe fo...

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Main Authors: N. I. Khokhlova, E. I. Krasnova, L. L. Pozdnyakova
Format: Article
Language:Russian
Published: Journal Infectology 2015-04-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/376
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author N. I. Khokhlova
E. I. Krasnova
L. L. Pozdnyakova
author_facet N. I. Khokhlova
E. I. Krasnova
L. L. Pozdnyakova
author_sort N. I. Khokhlova
collection DOAJ
description The paper presents the analysis of clinical and laboratory symptoms in 35 adult patients with denger fever, Novosibirsk residents, which travelled in endemic countries, mostly Tailand. The classic form of the disease was determined in all cases. The moderate form was in 71,5% patients, the severe form was in the rest ones. The diagnosis of dengue was verified by detection of specific immunoglobulin M and in some cases immunoglobulin G and also virus dengue NS1 antigen by immunochromatography. The dominant clinical symptoms in observed patients were fever for 3–8 days (100%), mostly high one (71,4%), asthenia (97,1%), anorexia (100%), myalgia or/and arthralgia (77,1%), exantema (60%), hepatomegaly (62,8%). The gematologic indicators were represented with thrombocytopenia in 91,4% patients (from 167 to 20×109/l) и leucopenia in 85,7% patients (from 3,9 to 1,1×109/l). The cytolitic syndrom was revealed in 80% patients with predominance of aspartate aminotransferase activity in early period of the disease.
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spelling doaj.art-4e4465d6039e406787f7a5eae678e0ec2023-09-02T11:46:03ZrusJournal InfectologyЖурнал инфектологии2072-67322015-04-0171656910.22625/2072-6732-2015-7-1-65-69390Clinical and laboratory diagnosis of dengue fever in travelersN. I. Khokhlova0E. I. Krasnova1L. L. Pozdnyakova2Новосибирский государственный медицинский университет, Новосибирск, РоссияНовосибирский государственный медицинский университет, Новосибирск, РоссияГородская инфекционная клиническая больница No 1, Новосибирск, РоссияThe paper presents the analysis of clinical and laboratory symptoms in 35 adult patients with denger fever, Novosibirsk residents, which travelled in endemic countries, mostly Tailand. The classic form of the disease was determined in all cases. The moderate form was in 71,5% patients, the severe form was in the rest ones. The diagnosis of dengue was verified by detection of specific immunoglobulin M and in some cases immunoglobulin G and also virus dengue NS1 antigen by immunochromatography. The dominant clinical symptoms in observed patients were fever for 3–8 days (100%), mostly high one (71,4%), asthenia (97,1%), anorexia (100%), myalgia or/and arthralgia (77,1%), exantema (60%), hepatomegaly (62,8%). The gematologic indicators were represented with thrombocytopenia in 91,4% patients (from 167 to 20×109/l) и leucopenia in 85,7% patients (from 3,9 to 1,1×109/l). The cytolitic syndrom was revealed in 80% patients with predominance of aspartate aminotransferase activity in early period of the disease.https://journal.niidi.ru/jofin/article/view/376лихорадка денгеклиническая и лабораторная диагностика
spellingShingle N. I. Khokhlova
E. I. Krasnova
L. L. Pozdnyakova
Clinical and laboratory diagnosis of dengue fever in travelers
Журнал инфектологии
лихорадка денге
клиническая и лабораторная диагностика
title Clinical and laboratory diagnosis of dengue fever in travelers
title_full Clinical and laboratory diagnosis of dengue fever in travelers
title_fullStr Clinical and laboratory diagnosis of dengue fever in travelers
title_full_unstemmed Clinical and laboratory diagnosis of dengue fever in travelers
title_short Clinical and laboratory diagnosis of dengue fever in travelers
title_sort clinical and laboratory diagnosis of dengue fever in travelers
topic лихорадка денге
клиническая и лабораторная диагностика
url https://journal.niidi.ru/jofin/article/view/376
work_keys_str_mv AT nikhokhlova clinicalandlaboratorydiagnosisofdenguefeverintravelers
AT eikrasnova clinicalandlaboratorydiagnosisofdenguefeverintravelers
AT llpozdnyakova clinicalandlaboratorydiagnosisofdenguefeverintravelers