Phosphorylation of CREB-Specific Coactivator CRTC2 at Ser238 Promotes Proliferation, Migration, and Invasion of Colorectal Cancer Cells

Phosphorylation of CREB-Specific Coactivator CRTC2 at Ser238 Promotes Proliferation, Migration, and Invasion of Colorectal Cancer Cells

cAMP response element binding protein (CREB)-regulated transcription coactivator 2 (CRTC2), a member of the novel CRTC family of transcriptional coactivators that activates basic leucine zipper transcription factors, including CREB, is overexpressed in many carcinomas, including colon cancer. Phosph...

Bibliografske podrobnosti
Main Authors:	Yi Wang MD, Qian Liu MD, Hanshuo Zhang PhD
Format:	Article
Jezik:	English
Izdano:	SAGE Publishing 2020-09-01
Serija:	Technology in Cancer Research & Treatment
Online dostop:	https://doi.org/10.1177/1533033820962111

Podobne knjige/članki

Uncovering the function of CREB regulated transcription coactivator 2 (CRTC2) in rodent brain
od: Lim, Wei Lee
Izdano: (2018)

Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment
od: Tim Sonntag, et al.
Izdano: (2019-01-01)

Characterization of Creb-regulated transcription coactivator 1 (Crtc1) during embryogenesis of Zebrafish (Danio rerio)
od: Sie, Lawrence Eng Kean
Izdano: (2014)

CREB coactivator CRTC1 in melanocortin‐4 receptor‐expressing cells regulate dietary fat intake
od: Shigenobu Matsumura, et al.
Izdano: (2024-12-01)

The CREB Coactivator CRTC2 Is a Lymphoma Tumor Suppressor that Preserves Genome Integrity through Transcription of DNA Mismatch Repair Genes
od: Minggang Fang, et al.
Izdano: (2015-06-01)

Activation of the CREB Coactivator CRTC2 by Aberrant Mitogen Signaling promotes oncogenic functions in HPV16 positive head and neck cancer
od: Miranda B. Carper, et al.
Izdano: (2022-07-01)

Elucidation of the physical and functional interactions between the MEIS1A and the CREB and CRTC transcription factors
od: Looi, Yvonne
Izdano: (2012)

The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila
od: Youjie Yin, et al.
Izdano: (2022-08-01)

Dependency of human and murine LKB1-inactivated lung cancer on aberrant CRTC-CREB activation
od: Xin Zhou, et al.
Izdano: (2021-06-01)

Glucocorticoids Alter CRTC-CREB Signaling in Muscle Cells: Impact on PGC-1α Expression and Atrophy Markers.
od: Jill A Rahnert, et al.
Izdano: (2016-01-01)

A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex
od: Yaqiong Chen, et al.
Izdano: (2022-01-01)

CRTC2 activates the epithelial–mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway
od: Yujie Li, et al.
Izdano: (2023-10-01)

Anabolic and Pro-metabolic Functions of CREB-CRTC in Skeletal Muscle: Advantages and Obstacles for Type 2 Diabetes and Cancer Cachexia
od: Rebecca Berdeaux, et al.
Izdano: (2019-08-01)

The Transcription Factor Creb is Involved in Sorafenib-Inhibited Renal Cancer Cell Proliferation, Migration and Invasion
od: Huang Shuaishuai, et al.
Izdano: (2018-12-01)

Nuclear receptor coactivator 6 (NCoA6) promotes cell proliferation, migration, and invasion in pancreatic cancer
od: Xin Wang, et al.
Izdano: (2023-09-01)

SIK1 inhibits IL-1β-stimulated cartilage apoptosis and inflammation in vitro through the CRTC2/CREB1 signaling
od: Chen Mangmang, et al.
Izdano: (2025-03-01)

Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes
od: Geun Hyang Kim, et al.
Izdano: (2015-03-01)

Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus
od: Hyun Jung Kwon, et al.
Izdano: (2019-11-01)

PBK Enhances Cellular Proliferation With Histone H3 Phosphorylation and Suppresses Migration and Invasion With CDH1 Stabilization in Colorectal Cancer
od: Akira Koshino, et al.
Izdano: (2022-01-01)

Sustained CREB phosphorylation by lipid-peptide liquid crystalline nanoassemblies
od: Yu Wu, et al.
Izdano: (2023-11-01)

The Selective SIK2 Inhibitor ARN-3236 Produces Strong Antidepressant-Like Efficacy in Mice via the Hippocampal CRTC1-CREB-BDNF Pathway
od: Yue Liu, et al.
Izdano: (2021-01-01)

Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway
od: Shan Wu, et al.
Izdano: (2024-01-01)

LncRNA BLACAT1/miR-519d-3p/CREB1 Axis Mediates Proliferation, Apoptosis, Migration, Invasion, and Drug-Resistance in Colorectal Cancer Progression
od: Chen R, et al.
Izdano: (2020-12-01)

ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis.
od: Bandish Kapadia, et al.
Izdano: (2013-01-01)

The role of CRTC genes in the development of the zebrafish embryo
od: Fang, Trixy Xinyi
Izdano: (2012)

CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET
od: Shuyang Wang, et al.
Izdano: (2020-08-01)

Mucoepidermoid carcinoma of the lacrimal gland in a patient with the CRTC1-MAML2 fusion gene
od: Kensaku Makino, MD, et al.
Izdano: (2021-12-01)

The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells.
od: Xiaochao Tan, et al.
Izdano: (2012-01-01)

Regulation of CREB Phosphorylation in Nucleus Accumbens after Relief Conditioning
od: Elaheh Soleimanpour, et al.
Izdano: (2021-01-01)

RETRACTED: PAK5 facilitates the proliferation, invasion and migration in colorectal cancer cells
od: Silin Huang, et al.
Izdano: (2020-07-01)

Radish Seed Exerts Anti-Diabetic and Obesity-Reducing Effects in Mice by Promoting the Activation of Uncoupling Protein 1 and Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α
od: Yao-Chien Wang MD, et al.
Izdano: (2025-02-01)

Oxidative stress reprograms the transcriptional coactivator Yki to suppress cell proliferation
od: Xiaohan Sun, et al.
Izdano: (2024-08-01)

LncRNA PVT1 Promotes Cell Proliferation, Invasion, and Migration and Inhibits Cell Apoptosis by Phosphorylating YAP
od: Kaiyue Ji, et al.
Izdano: (2022-01-01)

Establishment and characterisation of CRTC1 knockout in rodent hippocampal neurons
od: Koh, Tyler Bo Kai
Izdano: (2017)

Sam68 promotes hepatic gluconeogenesis via CRTC2
od: Aijun Qiao, et al.
Izdano: (2021-06-01)

MiR-654-3p Constrains Proliferation, Invasion, and Migration of Sinonasal Squamous Cell Carcinoma via CREB1/PSEN1 Regulatory Axis
od: Xiao Cui, et al.
Izdano: (2022-01-01)

MiR-9-5p Inhibits the Proliferation, Migration and Invasion of Choroidal Melanoma by Targeting BRAF
od: Manman Ying MM, et al.
Izdano: (2020-11-01)

The role of peroxisome proliferator-activated receptor-coactivator-1 gene in skin aging
od: Shahrzad Aghaei, et al.
Izdano: (2016-01-01)

POLQ knockdown inhibits proliferation, migration, and invasion by inducing cell cycle arrest in colorectal cancer
od: Qing Yao, et al.
Izdano: (2024-11-01)

ZNF3 regulates proliferation, migration and invasion through MMP1 and TWIST in colorectal cancer
od: Du Le, et al.
Izdano: (2022-12-01)