Phosphorylation of CREB-Specific Coactivator CRTC2 at Ser238 Promotes Proliferation, Migration, and Invasion of Colorectal Cancer Cells

Phosphorylation of CREB-Specific Coactivator CRTC2 at Ser238 Promotes Proliferation, Migration, and Invasion of Colorectal Cancer Cells

cAMP response element binding protein (CREB)-regulated transcription coactivator 2 (CRTC2), a member of the novel CRTC family of transcriptional coactivators that activates basic leucine zipper transcription factors, including CREB, is overexpressed in many carcinomas, including colon cancer. Phosph...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Yi Wang MD, Qian Liu MD, Hanshuo Zhang PhD
Định dạng:	Bài viết
Ngôn ngữ:	English
Được phát hành:	SAGE Publishing 2020-09-01
Loạt:	Technology in Cancer Research & Treatment
Truy cập trực tuyến:	https://doi.org/10.1177/1533033820962111

Những quyển sách tương tự

Uncovering the function of CREB regulated transcription coactivator 2 (CRTC2) in rodent brain
Bằng: Lim, Wei Lee
Được phát hành: (2018)

Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment
Bằng: Tim Sonntag, et al.
Được phát hành: (2019-01-01)

Characterization of Creb-regulated transcription coactivator 1 (Crtc1) during embryogenesis of Zebrafish (Danio rerio)
Bằng: Sie, Lawrence Eng Kean
Được phát hành: (2014)

CREB coactivator CRTC1 in melanocortin‐4 receptor‐expressing cells regulate dietary fat intake
Bằng: Shigenobu Matsumura, et al.
Được phát hành: (2024-12-01)

The CREB Coactivator CRTC2 Is a Lymphoma Tumor Suppressor that Preserves Genome Integrity through Transcription of DNA Mismatch Repair Genes
Bằng: Minggang Fang, et al.
Được phát hành: (2015-06-01)

Activation of the CREB Coactivator CRTC2 by Aberrant Mitogen Signaling promotes oncogenic functions in HPV16 positive head and neck cancer
Bằng: Miranda B. Carper, et al.
Được phát hành: (2022-07-01)

Elucidation of the physical and functional interactions between the MEIS1A and the CREB and CRTC transcription factors
Bằng: Looi, Yvonne
Được phát hành: (2012)

The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila
Bằng: Youjie Yin, et al.
Được phát hành: (2022-08-01)

Dependency of human and murine LKB1-inactivated lung cancer on aberrant CRTC-CREB activation
Bằng: Xin Zhou, et al.
Được phát hành: (2021-06-01)

Glucocorticoids Alter CRTC-CREB Signaling in Muscle Cells: Impact on PGC-1α Expression and Atrophy Markers.
Bằng: Jill A Rahnert, et al.
Được phát hành: (2016-01-01)

A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex
Bằng: Yaqiong Chen, et al.
Được phát hành: (2022-01-01)

CRTC2 activates the epithelial–mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway
Bằng: Yujie Li, et al.
Được phát hành: (2023-10-01)

Anabolic and Pro-metabolic Functions of CREB-CRTC in Skeletal Muscle: Advantages and Obstacles for Type 2 Diabetes and Cancer Cachexia
Bằng: Rebecca Berdeaux, et al.
Được phát hành: (2019-08-01)

The Transcription Factor Creb is Involved in Sorafenib-Inhibited Renal Cancer Cell Proliferation, Migration and Invasion
Bằng: Huang Shuaishuai, et al.
Được phát hành: (2018-12-01)

Nuclear receptor coactivator 6 (NCoA6) promotes cell proliferation, migration, and invasion in pancreatic cancer
Bằng: Xin Wang, et al.
Được phát hành: (2023-09-01)

SIK1 inhibits IL-1β-stimulated cartilage apoptosis and inflammation in vitro through the CRTC2/CREB1 signaling
Bằng: Chen Mangmang, et al.
Được phát hành: (2025-03-01)

Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes
Bằng: Geun Hyang Kim, et al.
Được phát hành: (2015-03-01)

Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus
Bằng: Hyun Jung Kwon, et al.
Được phát hành: (2019-11-01)

PBK Enhances Cellular Proliferation With Histone H3 Phosphorylation and Suppresses Migration and Invasion With CDH1 Stabilization in Colorectal Cancer
Bằng: Akira Koshino, et al.
Được phát hành: (2022-01-01)

Sustained CREB phosphorylation by lipid-peptide liquid crystalline nanoassemblies
Bằng: Yu Wu, et al.
Được phát hành: (2023-11-01)

The Selective SIK2 Inhibitor ARN-3236 Produces Strong Antidepressant-Like Efficacy in Mice via the Hippocampal CRTC1-CREB-BDNF Pathway
Bằng: Yue Liu, et al.
Được phát hành: (2021-01-01)

Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway
Bằng: Shan Wu, et al.
Được phát hành: (2024-01-01)

LncRNA BLACAT1/miR-519d-3p/CREB1 Axis Mediates Proliferation, Apoptosis, Migration, Invasion, and Drug-Resistance in Colorectal Cancer Progression
Bằng: Chen R, et al.
Được phát hành: (2020-12-01)

ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis.
Bằng: Bandish Kapadia, et al.
Được phát hành: (2013-01-01)

The role of CRTC genes in the development of the zebrafish embryo
Bằng: Fang, Trixy Xinyi
Được phát hành: (2012)

CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET
Bằng: Shuyang Wang, et al.
Được phát hành: (2020-08-01)

Mucoepidermoid carcinoma of the lacrimal gland in a patient with the CRTC1-MAML2 fusion gene
Bằng: Kensaku Makino, MD, et al.
Được phát hành: (2021-12-01)

The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells.
Bằng: Xiaochao Tan, et al.
Được phát hành: (2012-01-01)

Regulation of CREB Phosphorylation in Nucleus Accumbens after Relief Conditioning
Bằng: Elaheh Soleimanpour, et al.
Được phát hành: (2021-01-01)

RETRACTED: PAK5 facilitates the proliferation, invasion and migration in colorectal cancer cells
Bằng: Silin Huang, et al.
Được phát hành: (2020-07-01)

Radish Seed Exerts Anti-Diabetic and Obesity-Reducing Effects in Mice by Promoting the Activation of Uncoupling Protein 1 and Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α
Bằng: Yao-Chien Wang MD, et al.
Được phát hành: (2025-02-01)

Oxidative stress reprograms the transcriptional coactivator Yki to suppress cell proliferation
Bằng: Xiaohan Sun, et al.
Được phát hành: (2024-08-01)

LncRNA PVT1 Promotes Cell Proliferation, Invasion, and Migration and Inhibits Cell Apoptosis by Phosphorylating YAP
Bằng: Kaiyue Ji, et al.
Được phát hành: (2022-01-01)

Establishment and characterisation of CRTC1 knockout in rodent hippocampal neurons
Bằng: Koh, Tyler Bo Kai
Được phát hành: (2017)

Sam68 promotes hepatic gluconeogenesis via CRTC2
Bằng: Aijun Qiao, et al.
Được phát hành: (2021-06-01)

MiR-654-3p Constrains Proliferation, Invasion, and Migration of Sinonasal Squamous Cell Carcinoma via CREB1/PSEN1 Regulatory Axis
Bằng: Xiao Cui, et al.
Được phát hành: (2022-01-01)

MiR-9-5p Inhibits the Proliferation, Migration and Invasion of Choroidal Melanoma by Targeting BRAF
Bằng: Manman Ying MM, et al.
Được phát hành: (2020-11-01)

The role of peroxisome proliferator-activated receptor-coactivator-1 gene in skin aging
Bằng: Shahrzad Aghaei, et al.
Được phát hành: (2016-01-01)

POLQ knockdown inhibits proliferation, migration, and invasion by inducing cell cycle arrest in colorectal cancer
Bằng: Qing Yao, et al.
Được phát hành: (2024-11-01)

ZNF3 regulates proliferation, migration and invasion through MMP1 and TWIST in colorectal cancer
Bằng: Du Le, et al.
Được phát hành: (2022-12-01)