Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma Screening
We aimed to evaluate the accuracy of glaucoma screening using fundus photography combined with optical coherence tomography and determine the agreement between ophthalmologists and ophthalmology residents. We used a comprehensive ophthalmologic examination dataset obtained from 503 cases (1006 eyes)...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/5/1100 |
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| author | Tomoyuki Watanabe Yoshimune Hiratsuka Yoshiyuki Kita Hiroshi Tamura Ryo Kawasaki Tetsuji Yokoyama Motoko Kawashima Tadashi Nakano Masakazu Yamada |
| author_facet | Tomoyuki Watanabe Yoshimune Hiratsuka Yoshiyuki Kita Hiroshi Tamura Ryo Kawasaki Tetsuji Yokoyama Motoko Kawashima Tadashi Nakano Masakazu Yamada |
| author_sort | Tomoyuki Watanabe |
| collection | DOAJ |
| description | We aimed to evaluate the accuracy of glaucoma screening using fundus photography combined with optical coherence tomography and determine the agreement between ophthalmologists and ophthalmology residents. We used a comprehensive ophthalmologic examination dataset obtained from 503 cases (1006 eyes). Of the 1006 eyes, 132 had a confirmed glaucoma diagnosis. Overall, 24 doctors, comprising two groups (ophthalmologists and ophthalmology residents, 12 individuals/group), analyzed the data presented in three screening strategies as follows: (1) fundus photography alone, (2) fundus photography + optical coherence tomography, and (3) fundus photography + optical coherence tomography + comprehensive examination. We investigated the diagnostic accuracy (sensitivity and specificity). The respective sensitivity and specificity values for the diagnostic accuracy obtained by 24 doctors, 12 ophthalmologists, and 12 ophthalmology residents were as follows: (1) fundus photography: sensitivity, 55.4%, 55.4%, and 55.4%; specificity, 91.8%, 94.0%, and 89.6%; (2) fundus photography + OCT: sensitivity, 80.0%, 82.3%, and 77.8%; specificity, 91.7%, 92.9%, and 90.6%; and (3) fundus photography + OCT + comprehensive examination: sensitivity 78.4%, 79.8%, and 77.1%; specificity, 92.7%, 94.0%, and 91.3%. The diagnostic accuracy of glaucoma screening significantly increased with optical coherence tomography. Following its addition, ophthalmologists could more effectively improve the diagnostic accuracy than ophthalmology residents. Screening accuracy is improved when optical coherence tomography is added to fundus photography. |
| first_indexed | 2024-03-10T03:02:48Z |
| format | Article |
| id | doaj.art-4e50870bbd5f4145986c690d919cf69f |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T03:02:48Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-4e50870bbd5f4145986c690d919cf69f2023-11-23T10:39:21ZengMDPI AGDiagnostics2075-44182022-04-01125110010.3390/diagnostics12051100Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma ScreeningTomoyuki Watanabe0Yoshimune Hiratsuka1Yoshiyuki Kita2Hiroshi Tamura3Ryo Kawasaki4Tetsuji Yokoyama5Motoko Kawashima6Tadashi Nakano7Masakazu Yamada8Department of Ophthalmology, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Ophthalmology, Juntendo University School of Medicine, Tokyo 113-8421, JapanDepartment of Ophthalmology, Kyorin University School of Medicine, Tokyo 181-8611, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto 606-8507, JapanArtificial Intelligence Center for Medical Research and Application, Osaka University Hospital, Suita 565-0871, JapanDepartment of Health Promotion, National Institute of Public Health, Wako 351-0197, JapanDepartment of Ophthalmology, Keio University School of Medicine, Tokyo 160-8582, JapanDepartment of Ophthalmology, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Ophthalmology, Kyorin University School of Medicine, Tokyo 181-8611, JapanWe aimed to evaluate the accuracy of glaucoma screening using fundus photography combined with optical coherence tomography and determine the agreement between ophthalmologists and ophthalmology residents. We used a comprehensive ophthalmologic examination dataset obtained from 503 cases (1006 eyes). Of the 1006 eyes, 132 had a confirmed glaucoma diagnosis. Overall, 24 doctors, comprising two groups (ophthalmologists and ophthalmology residents, 12 individuals/group), analyzed the data presented in three screening strategies as follows: (1) fundus photography alone, (2) fundus photography + optical coherence tomography, and (3) fundus photography + optical coherence tomography + comprehensive examination. We investigated the diagnostic accuracy (sensitivity and specificity). The respective sensitivity and specificity values for the diagnostic accuracy obtained by 24 doctors, 12 ophthalmologists, and 12 ophthalmology residents were as follows: (1) fundus photography: sensitivity, 55.4%, 55.4%, and 55.4%; specificity, 91.8%, 94.0%, and 89.6%; (2) fundus photography + OCT: sensitivity, 80.0%, 82.3%, and 77.8%; specificity, 91.7%, 92.9%, and 90.6%; and (3) fundus photography + OCT + comprehensive examination: sensitivity 78.4%, 79.8%, and 77.1%; specificity, 92.7%, 94.0%, and 91.3%. The diagnostic accuracy of glaucoma screening significantly increased with optical coherence tomography. Following its addition, ophthalmologists could more effectively improve the diagnostic accuracy than ophthalmology residents. Screening accuracy is improved when optical coherence tomography is added to fundus photography.https://www.mdpi.com/2075-4418/12/5/1100diagnostic accuracyglaucomaoptical coherence tomographyophthalmologistscreening |
| spellingShingle | Tomoyuki Watanabe Yoshimune Hiratsuka Yoshiyuki Kita Hiroshi Tamura Ryo Kawasaki Tetsuji Yokoyama Motoko Kawashima Tadashi Nakano Masakazu Yamada Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma Screening Diagnostics diagnostic accuracy glaucoma optical coherence tomography ophthalmologist screening |
| title | Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma Screening |
| title_full | Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma Screening |
| title_fullStr | Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma Screening |
| title_full_unstemmed | Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma Screening |
| title_short | Combining Optical Coherence Tomography and Fundus Photography to Improve Glaucoma Screening |
| title_sort | combining optical coherence tomography and fundus photography to improve glaucoma screening |
| topic | diagnostic accuracy glaucoma optical coherence tomography ophthalmologist screening |
| url | https://www.mdpi.com/2075-4418/12/5/1100 |
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