Combination of Pancreastatin inhibitor PSTi8 with metformin inhibits Fetuin-A in type 2 diabetic mice

Combination of Pancreastatin inhibitor PSTi8 with metformin inhibits Fetuin-A in type 2 diabetic mice

In the preceding study, we delineated that high-fat diet (HFD) consumption in mice increases the circulatory level of pancreastatin (PST), which additionally enhances the free fatty acid (FFA) concentration in circulation. Consequently, the aggravated FFA activates Fetuin-A, which facilitates hepati...

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Bibliographic Details
Main Authors: Pragati Singh, Richa Garg, Umesh K. Goand, Mohammed Riyazuddin, Mohammad Irshad Reza, Anees A. Syed, Anand P. Gupta, Athar Husain, Jiaur R. Gayen
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Heliyon
Subjects:
Diabetes
Fetuin-A
Combination therapy
PSTi8
Metformin
Insulin resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020319769

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