RuvBL1 Maintains Resistance to TRAIL-Induced Apoptosis by Suppressing c-Jun/AP-1 Activity in Non-Small Cell Lung Cancer

RuvBL1 Maintains Resistance to TRAIL-Induced Apoptosis by Suppressing c-Jun/AP-1 Activity in Non-Small Cell Lung Cancer

Lung cancer is the common malignant tumor with the highest death rate in the world. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as a potential anticancer agent induces selective apoptotic death of human cancer cells. Unfortunately, approximately half of lung cancer cell lines are...

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Bibliographic Details
Main Authors: Hao Li, Taoran Zhou, Yue Zhang, Hengyi Jiang, Jing Zhang, Zichun Hua
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
RuvBL1
TRAIL
c-Jun/AP-1
resistance
lung cancer
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.679243/full

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