Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2]
Introduction: Pulmonary alveolar microlithiasis (PAM) is an autosomal recessive disease characterized by the deposition of phosphate and calcium in the alveoli. The disease progresses asymptomatically until later stages. When it becomes symptomatic, lung transplantations performed before the onset o...
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| Format: | Article |
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F1000 Research Ltd
2014-05-01
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| Series: | F1000Research |
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| Online Access: | http://f1000research.com/articles/3-118/v1 |
| _version_ | 1818458290133139456 |
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| author | Bülent Güçyetmez Aylin Ogan Aylin Çimet Ayyıldız Berrin Yalçın Güder Walter Klepetko |
| author_facet | Bülent Güçyetmez Aylin Ogan Aylin Çimet Ayyıldız Berrin Yalçın Güder Walter Klepetko |
| author_sort | Bülent Güçyetmez |
| collection | DOAJ |
| description | Introduction: Pulmonary alveolar microlithiasis (PAM) is an autosomal recessive disease characterized by the deposition of phosphate and calcium in the alveoli. The disease progresses asymptomatically until later stages. When it becomes symptomatic, lung transplantations performed before the onset of right heart failure may improve life expectancy and quality. Here we present a case report concerning the very first Turkish PAM patient to have undergone lung transplantation surgery. Patient information: A 52 year-old female, Caucasian patient, already diagnosed with PAM in infancy, was admitted to the intensive care unit, diagnosed with pneumonia and hospitalized for 20 days. We decided to refer the patient to a specialized center for lung transplantation. Bilateral lung transplantation was performed in Vienna 14 months later and no recurrence was observed during the first postoperative year. Conclusion: Bilateral lung transplantation may improve both the life expectancy and the quality of life of PAM diagnosed patients with severe respiratory failure who do not suffer from right heart failure. The risk of recurrence should not be considered as a justifying reason to avoid transplantation as a treatment method. |
| first_indexed | 2024-12-14T22:56:06Z |
| format | Article |
| id | doaj.art-4e58667aa11144feba0911965f536c9c |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-14T22:56:06Z |
| publishDate | 2014-05-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-4e58667aa11144feba0911965f536c9c2022-12-21T22:44:34ZengF1000 Research LtdF1000Research2046-14022014-05-01310.12688/f1000research.4035.14322Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2]Bülent Güçyetmez0Aylin Ogan1Aylin Çimet Ayyıldız2Berrin Yalçın Güder3Walter Klepetko4Intensive Care Unit, International Hospital, Istanbul, 34149, TurkeyIntensive Care Unit, International Hospital, Istanbul, 34149, TurkeyIntensive Care Unit, International Hospital, Istanbul, 34149, TurkeyIntensive Care Unit, International Hospital, Istanbul, 34149, TurkeyDivision of Thoracic Surgery, Medical University of Vienna, Vienna, A-1090, AustriaIntroduction: Pulmonary alveolar microlithiasis (PAM) is an autosomal recessive disease characterized by the deposition of phosphate and calcium in the alveoli. The disease progresses asymptomatically until later stages. When it becomes symptomatic, lung transplantations performed before the onset of right heart failure may improve life expectancy and quality. Here we present a case report concerning the very first Turkish PAM patient to have undergone lung transplantation surgery. Patient information: A 52 year-old female, Caucasian patient, already diagnosed with PAM in infancy, was admitted to the intensive care unit, diagnosed with pneumonia and hospitalized for 20 days. We decided to refer the patient to a specialized center for lung transplantation. Bilateral lung transplantation was performed in Vienna 14 months later and no recurrence was observed during the first postoperative year. Conclusion: Bilateral lung transplantation may improve both the life expectancy and the quality of life of PAM diagnosed patients with severe respiratory failure who do not suffer from right heart failure. The risk of recurrence should not be considered as a justifying reason to avoid transplantation as a treatment method.http://f1000research.com/articles/3-118/v1Interstitial Lung DiseasesRespiratory Problems in Critical Care |
| spellingShingle | Bülent Güçyetmez Aylin Ogan Aylin Çimet Ayyıldız Berrin Yalçın Güder Walter Klepetko Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2] F1000Research Interstitial Lung Diseases Respiratory Problems in Critical Care |
| title | Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2] |
| title_full | Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2] |
| title_fullStr | Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2] |
| title_full_unstemmed | Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2] |
| title_short | Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2] |
| title_sort | lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis a case report v1 ref status indexed http f1000r es 3c2 |
| topic | Interstitial Lung Diseases Respiratory Problems in Critical Care |
| url | http://f1000research.com/articles/3-118/v1 |
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