Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease
As the number of individuals, particularly the elderly, using herbal products with prescription drugs continues to grow, the risk for adverse interactions increases but remains poorly recognized. The true incidence and nature of adverse herb reactions or herb-drug interactions remains unknown since...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Advocate Aurora Health
2015-11-01
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| Series: | Journal of Patient-Centered Research and Reviews |
| Subjects: | |
| Online Access: | http://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1212&context=jpcrr |
| _version_ | 1828044034846752768 |
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| author | Sulaiman Sultan Maria Viqar Rabaiya Ali A. Jamil Tajik Arshad Jahangir |
| author_facet | Sulaiman Sultan Maria Viqar Rabaiya Ali A. Jamil Tajik Arshad Jahangir |
| author_sort | Sulaiman Sultan |
| collection | DOAJ |
| description | As the number of individuals, particularly the elderly, using herbal products with prescription drugs continues to grow, the risk for adverse interactions increases but remains poorly recognized. The true incidence and nature of adverse herb reactions or herb-drug interactions remains unknown since no postmarketing surveillance mechanism exists. Adverse events are greatly underreported, and information regarding safety mainly comes from case reports and suboptimally conducted studies in a limited number of healthy young volunteers or patients with limited comorbidities. Therefore, convincing evidence for the safety of herbal products in the elderly is lacking, and the true magnitude of problems that herb-drug interactions pose to public health, particularly in elderly patients with cardiovascular diseases, is not known. Since cardiovascular diseases themselves are life threatening, necessitate use of multiple medications and occur in a population with extensive comorbidities, the risk of herb-drug and herb-disease interactions is not minor and cannot be ignored. This review addresses these concerns in an effort to raise awareness about the use of herbal medicine by the elderly and its potential adverse impact on the efficacy of prescription medications that can increase predisposition to catastrophic events such as major bleeding, inadequate anticoagulation leading to undesired clotting, transplant organ rejection and life-threatening cardiac arrhythmias. |
| first_indexed | 2024-04-10T17:50:42Z |
| format | Article |
| id | doaj.art-4e5b12b8d93943ad8ae3c352a8eef5dc |
| institution | Directory Open Access Journal |
| issn | 2330-0698 2330-0698 |
| language | English |
| last_indexed | 2024-04-10T17:50:42Z |
| publishDate | 2015-11-01 |
| publisher | Advocate Aurora Health |
| record_format | Article |
| series | Journal of Patient-Centered Research and Reviews |
| spelling | doaj.art-4e5b12b8d93943ad8ae3c352a8eef5dc2023-02-02T21:55:06ZengAdvocate Aurora HealthJournal of Patient-Centered Research and Reviews2330-06982330-06982015-11-012417419110.17294/2330-0698.1212Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular DiseaseSulaiman Sultan0Maria Viqar1Rabaiya Ali2A. Jamil Tajik3Arshad Jahangir4Aurora Health CareDallas Medical Physician GroupAurora Health CareAurora Cardiovascular Services, Aurora Health CareSheikh Khalifa bin Hamad Al Thani Center for Integrative Research on Cardiovascular Aging, Aurora Research Institute, Aurora Health CareAs the number of individuals, particularly the elderly, using herbal products with prescription drugs continues to grow, the risk for adverse interactions increases but remains poorly recognized. The true incidence and nature of adverse herb reactions or herb-drug interactions remains unknown since no postmarketing surveillance mechanism exists. Adverse events are greatly underreported, and information regarding safety mainly comes from case reports and suboptimally conducted studies in a limited number of healthy young volunteers or patients with limited comorbidities. Therefore, convincing evidence for the safety of herbal products in the elderly is lacking, and the true magnitude of problems that herb-drug interactions pose to public health, particularly in elderly patients with cardiovascular diseases, is not known. Since cardiovascular diseases themselves are life threatening, necessitate use of multiple medications and occur in a population with extensive comorbidities, the risk of herb-drug and herb-disease interactions is not minor and cannot be ignored. This review addresses these concerns in an effort to raise awareness about the use of herbal medicine by the elderly and its potential adverse impact on the efficacy of prescription medications that can increase predisposition to catastrophic events such as major bleeding, inadequate anticoagulation leading to undesired clotting, transplant organ rejection and life-threatening cardiac arrhythmias.http://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1212&context=jpcrrcomplementary therapyherbsintegrative medicinecardiovascular agentselderlyherb-drug interaction |
| spellingShingle | Sulaiman Sultan Maria Viqar Rabaiya Ali A. Jamil Tajik Arshad Jahangir Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease Journal of Patient-Centered Research and Reviews complementary therapy herbs integrative medicine cardiovascular agents elderly herb-drug interaction |
| title | Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease |
| title_full | Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease |
| title_fullStr | Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease |
| title_full_unstemmed | Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease |
| title_short | Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease |
| title_sort | essentials of herb drug interactions in the elderly with cardiovascular disease |
| topic | complementary therapy herbs integrative medicine cardiovascular agents elderly herb-drug interaction |
| url | http://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1212&context=jpcrr |
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