Progress in the study of aging marker criteria in human populations
The use of human aging markers, which are physiological, biochemical and molecular indicators of structural or functional degeneration associated with aging, is the fundamental basis of individualized aging assessments. Identifying methods for selecting markers has become a primary and vital aspect...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1305303/full |
| _version_ | 1827375666763399168 |
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| author | Yan He Yan He Zhe Li Yue Niu Yuting Duan Qian Wang Xiaomin Liu Zheyi Dong Ying Zheng Yizhi Chen Yizhi Chen Yong Wang Delong Zhao Xuefeng Sun Guangyan Cai Zhe Feng Weiguang Zhang Xiangmei Chen Xiangmei Chen |
| author_facet | Yan He Yan He Zhe Li Yue Niu Yuting Duan Qian Wang Xiaomin Liu Zheyi Dong Ying Zheng Yizhi Chen Yizhi Chen Yong Wang Delong Zhao Xuefeng Sun Guangyan Cai Zhe Feng Weiguang Zhang Xiangmei Chen Xiangmei Chen |
| author_sort | Yan He |
| collection | DOAJ |
| description | The use of human aging markers, which are physiological, biochemical and molecular indicators of structural or functional degeneration associated with aging, is the fundamental basis of individualized aging assessments. Identifying methods for selecting markers has become a primary and vital aspect of aging research. However, there is no clear consensus or uniform principle on the criteria for screening aging markers. Therefore, we combine previous research from our center and summarize the criteria for screening aging markers in previous population studies, which are discussed in three aspects: functional perspective, operational implementation perspective and methodological perspective. Finally, an evaluation framework has been established, and the criteria are categorized into three levels based on their importance, which can help assess the extent to which a candidate biomarker may be feasible, valid, and useful for a specific use context. |
| first_indexed | 2024-03-08T11:55:18Z |
| format | Article |
| id | doaj.art-4e5b9d791a7740f59928b2e90e439109 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-03-08T11:55:18Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-4e5b9d791a7740f59928b2e90e4391092024-01-24T04:36:34ZengFrontiers Media S.A.Frontiers in Public Health2296-25652024-01-011210.3389/fpubh.2024.13053031305303Progress in the study of aging marker criteria in human populationsYan He0Yan He1Zhe Li2Yue Niu3Yuting Duan4Qian Wang5Xiaomin Liu6Zheyi Dong7Ying Zheng8Yizhi Chen9Yizhi Chen10Yong Wang11Delong Zhao12Xuefeng Sun13Guangyan Cai14Zhe Feng15Weiguang Zhang16Xiangmei Chen17Xiangmei Chen18Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaThe First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Academician Team Innovation Center, Sanya, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaChengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases Research, Beijing, ChinaThe use of human aging markers, which are physiological, biochemical and molecular indicators of structural or functional degeneration associated with aging, is the fundamental basis of individualized aging assessments. Identifying methods for selecting markers has become a primary and vital aspect of aging research. However, there is no clear consensus or uniform principle on the criteria for screening aging markers. Therefore, we combine previous research from our center and summarize the criteria for screening aging markers in previous population studies, which are discussed in three aspects: functional perspective, operational implementation perspective and methodological perspective. Finally, an evaluation framework has been established, and the criteria are categorized into three levels based on their importance, which can help assess the extent to which a candidate biomarker may be feasible, valid, and useful for a specific use context.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1305303/fullmarkeragingaging markershumanbiological agechronological age |
| spellingShingle | Yan He Yan He Zhe Li Yue Niu Yuting Duan Qian Wang Xiaomin Liu Zheyi Dong Ying Zheng Yizhi Chen Yizhi Chen Yong Wang Delong Zhao Xuefeng Sun Guangyan Cai Zhe Feng Weiguang Zhang Xiangmei Chen Xiangmei Chen Progress in the study of aging marker criteria in human populations Frontiers in Public Health marker aging aging markers human biological age chronological age |
| title | Progress in the study of aging marker criteria in human populations |
| title_full | Progress in the study of aging marker criteria in human populations |
| title_fullStr | Progress in the study of aging marker criteria in human populations |
| title_full_unstemmed | Progress in the study of aging marker criteria in human populations |
| title_short | Progress in the study of aging marker criteria in human populations |
| title_sort | progress in the study of aging marker criteria in human populations |
| topic | marker aging aging markers human biological age chronological age |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1305303/full |
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