Methylated Cytochrome P450 and the Solute Carrier Family of Genes Correlate With Perturbations in Bile Acid Metabolism in Parkinson’s Disease

Methylated Cytochrome P450 and the Solute Carrier Family of Genes Correlate With Perturbations in Bile Acid Metabolism in Parkinson’s Disease

Parkinson’s disease (PD) is second most prevalent neurodegenerative disorder following Alzheimer’s disease. Parkinson’s disease is hypothesized to be caused by a multifaceted interplay between genetic and environmental factors. Herein, and for the first time, we describe the integration of metabolom...

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Bibliographic Details
Main Authors: Sangeetha Vishweswaraiah, Sumeyya Akyol, Ali Yilmaz, Zafer Ugur, Juozas Gordevičius, Kyung Joon Oh, Patrik Brundin, Uppala Radhakrishna, Viviane Labrie, Stewart F. Graham
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Neuroscience
Subjects:
metabolomics
epigenetics
integrative omics
epimetabolomics
Parkinson’s disease
etiopathophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.804261/full

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