Losartan Attenuates Insulin Resistance and Regulates Browning Phenomenon of White Adipose Tissue in <i>ob</i><i>/ob</i> Mice

Insulin resistance (IR) is a villain role to the pathology of fatty liver diseases implicated in adipose tissue dysfunction, which is characterized by lipid droplets (LDs) accumulation and hypoxia-inducible factor 1α (HIF1α) related macrophage infiltration. HIF1α is required for its lipogenic action...

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Bibliographic Details
Main Authors: Hsuan-Miao Liu, Cheng-Hui Wang, Zi-Yu Chang, Tse-Hung Huang, Tzung-Yan Lee
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/43/3/128