Losartan Attenuates Insulin Resistance and Regulates Browning Phenomenon of White Adipose Tissue in <i>ob</i><i>/ob</i> Mice
Insulin resistance (IR) is a villain role to the pathology of fatty liver diseases implicated in adipose tissue dysfunction, which is characterized by lipid droplets (LDs) accumulation and hypoxia-inducible factor 1α (HIF1α) related macrophage infiltration. HIF1α is required for its lipogenic action...
Main Authors: | Hsuan-Miao Liu, Cheng-Hui Wang, Zi-Yu Chang, Tse-Hung Huang, Tzung-Yan Lee |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-10-01
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Series: | Current Issues in Molecular Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/1467-3045/43/3/128 |
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