Prevalence of <it>aac(6')-Ib-cr </it>plasmid-mediated and chromosome-encoded fluoroquinolone resistance in <it>Enterobacteriaceae </it>in Italy
<p>Abstract</p> <p>The spread of <it>aac(6')-Ib-cr </it>plasmid-mediated quinolone resistance determinants was evaluated in 197 enterobacterial isolates recovered in an Italian teaching hospital. The <it>aac(6')-Ib-cr </it>gene was found exclusivel...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-08-01
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| Series: | Gut Pathogens |
| Subjects: | |
| Online Access: | http://www.gutpathogens.com/content/3/1/12 |
| Summary: | <p>Abstract</p> <p>The spread of <it>aac(6')-Ib-cr </it>plasmid-mediated quinolone resistance determinants was evaluated in 197 enterobacterial isolates recovered in an Italian teaching hospital. The <it>aac(6')-Ib-cr </it>gene was found exclusively in <it>Escherichia coli </it>strains. The gene was located on a plasmid which presented additional ESBL genes. Most of the clinical strains were clonally related and displayed three point mutations at the topoisomerase level which conferred high resistance to fluoroquinolones.</p> |
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| ISSN: | 1757-4749 |