Induction Regimen in High-Risk Neuroblastoma: A Pilot Study of Highly Effective Continuous Exposure of Tumor Cells to Radio-Chemotherapy Sequence for 1 Month. The Critical Role of Iodine-131-Metaiodobenzylguanidine

Induction Regimen in High-Risk Neuroblastoma: A Pilot Study of Highly Effective Continuous Exposure of Tumor Cells to Radio-Chemotherapy Sequence for 1 Month. The Critical Role of Iodine-131-Metaiodobenzylguanidine

The prognosis of high-risk neuroblastoma (NB) continues to be poor. The early development of resistance often leads to disease recurrence. In the present study, an innovative induction regimen, including an intensive initial radio-chemotherapy sequence based on the use of iodine-131-metaiodobenzylgu...

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Bibliographic Details
Main Authors: Stefano Mastrangelo, Giorgio Attinà, Luca Zagaria, Alberto Romano, Antonio Ruggiero
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
high-risk neuroblastoma
induction treatment
chemotherapy
131-I-metaiodobenzylguanidine (131-I-MIBG)
radio-chemotherapy
Online Access:https://www.mdpi.com/2072-6694/14/20/5170

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