Nano TiO2/SiO2: An efficient and reusable catalyst for the synthesis of oxindole derivatives
Nano TiO2 supported on SiO2 (Nano TiO2/SiO2) as a solid Lewis acid, was found to be an effective and reusable catalyst for the condensation reaction of indoles with isatins to afford the corresponding bis(indolyl)oxindoles at 50 °C under solvent-free conditions. The efficacy of the catalyst was also...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-01-01
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| Series: | Journal of Saudi Chemical Society |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319610314001306 |
| _version_ | 1818318932147175424 |
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| author | Maryam Haghighi Kobra Nikoofar |
| author_facet | Maryam Haghighi Kobra Nikoofar |
| author_sort | Maryam Haghighi |
| collection | DOAJ |
| description | Nano TiO2 supported on SiO2 (Nano TiO2/SiO2) as a solid Lewis acid, was found to be an effective and reusable catalyst for the condensation reaction of indoles with isatins to afford the corresponding bis(indolyl)oxindoles at 50 °C under solvent-free conditions. The efficacy of the catalyst was also examined in the reaction of pyrrole and 3-methylindole with isatin. The catalyst has been recovered and its reusability confirmed in 5 runs. A plausible mechanism of condensation has also been suggested. |
| first_indexed | 2024-12-13T10:01:04Z |
| format | Article |
| id | doaj.art-4e6ad028ed6f45cda2e4d78a9d13b7c0 |
| institution | Directory Open Access Journal |
| issn | 1319-6103 |
| language | English |
| last_indexed | 2024-12-13T10:01:04Z |
| publishDate | 2016-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Saudi Chemical Society |
| spelling | doaj.art-4e6ad028ed6f45cda2e4d78a9d13b7c02022-12-21T23:51:39ZengElsevierJournal of Saudi Chemical Society1319-61032016-01-0120110110610.1016/j.jscs.2014.09.002Nano TiO2/SiO2: An efficient and reusable catalyst for the synthesis of oxindole derivativesMaryam HaghighiKobra NikoofarNano TiO2 supported on SiO2 (Nano TiO2/SiO2) as a solid Lewis acid, was found to be an effective and reusable catalyst for the condensation reaction of indoles with isatins to afford the corresponding bis(indolyl)oxindoles at 50 °C under solvent-free conditions. The efficacy of the catalyst was also examined in the reaction of pyrrole and 3-methylindole with isatin. The catalyst has been recovered and its reusability confirmed in 5 runs. A plausible mechanism of condensation has also been suggested.http://www.sciencedirect.com/science/article/pii/S1319610314001306Nano TiO2OxindoleIsatinIndoleReusable catalyst |
| spellingShingle | Maryam Haghighi Kobra Nikoofar Nano TiO2/SiO2: An efficient and reusable catalyst for the synthesis of oxindole derivatives Journal of Saudi Chemical Society Nano TiO2 Oxindole Isatin Indole Reusable catalyst |
| title | Nano TiO2/SiO2: An efficient and reusable catalyst for the synthesis of oxindole derivatives |
| title_full | Nano TiO2/SiO2: An efficient and reusable catalyst for the synthesis of oxindole derivatives |
| title_fullStr | Nano TiO2/SiO2: An efficient and reusable catalyst for the synthesis of oxindole derivatives |
| title_full_unstemmed | Nano TiO2/SiO2: An efficient and reusable catalyst for the synthesis of oxindole derivatives |
| title_short | Nano TiO2/SiO2: An efficient and reusable catalyst for the synthesis of oxindole derivatives |
| title_sort | nano tio2 sio2 an efficient and reusable catalyst for the synthesis of oxindole derivatives |
| topic | Nano TiO2 Oxindole Isatin Indole Reusable catalyst |
| url | http://www.sciencedirect.com/science/article/pii/S1319610314001306 |
| work_keys_str_mv | AT maryamhaghighi nanotio2sio2anefficientandreusablecatalystforthesynthesisofoxindolederivatives AT kobranikoofar nanotio2sio2anefficientandreusablecatalystforthesynthesisofoxindolederivatives |