Antimicrobial Effect of Hydroalcoholic Extracts of Oak Jaft (Quercus Persica) and Echium Amoenum on Shigella Flexneri
Background and Objectives: Today, because of the spread of drug resistance and the prevalence of infectious diseases, the use of medicinal plants has increased. So, in this study, the antibacterial effect of hydroalcoholic extract of Oak jaft and Echium amoenum was investigated on Shigella flexneri....
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Qom University of Medical Sciences
2021-08-01
|
| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| Subjects: | |
| Online Access: | http://journal.muq.ac.ir/article-1-3142-en.html |
| _version_ | 1818574723263496192 |
|---|---|
| author | Marzieh An'aam Fatemeh Riyahi Zaniani Farid Shirmardi Dezaki |
| author_facet | Marzieh An'aam Fatemeh Riyahi Zaniani Farid Shirmardi Dezaki |
| author_sort | Marzieh An'aam |
| collection | DOAJ |
| description | Background and Objectives: Today, because of the spread of drug resistance and the prevalence of infectious diseases, the use of medicinal plants has increased. So, in this study, the antibacterial effect of hydroalcoholic extract of Oak jaft and Echium amoenum was investigated on Shigella flexneri.
Methods: In this study, hydroalcoholic extracts were extracted by maceration method and concentrated by rotary evaporator then dried immediately. Next, the antimicrobial effect of different dilutions of extracts on Shigella flexneri was investigated by disk diffusion and micro broth dilution methods and compared with two antibiotics, ciprofloxacin and trimethoprim-sulfamethoxazole.
Results: The results showed that in proportion to the increase in the concentration of oak jaft extract, its antibacterial effect on Shigella flexneri also increased and 3.9 and 7.8 mg/ml of the extract were obtained by MIC and MBC dilution micro broth method, respectively. In the case of Echium amoenum extract, bacteria were grown at all dilutions (except the main stock of the extract (250 mg/ml)) and the extract had no antimicrobial effect on Shigella flexneri.
Conclusion: According to the results of this study, oak jaft extract had a good inhibitory effect on Shigella flexneri and in comparison, with ciprofloxacin antibiotic, a similar inhibitory effect was observed and in comparison, with trimethoprim sulfamethoxazole, more inhibitory effect was observed. |
| first_indexed | 2024-12-15T00:30:19Z |
| format | Article |
| id | doaj.art-4e6b625c16f14fd889af35958bef6ee1 |
| institution | Directory Open Access Journal |
| issn | 1735-7799 2008-1375 |
| language | fas |
| last_indexed | 2024-12-15T00:30:19Z |
| publishDate | 2021-08-01 |
| publisher | Qom University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum |
| spelling | doaj.art-4e6b625c16f14fd889af35958bef6ee12022-12-21T22:42:01ZfasQom University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum1735-77992008-13752021-08-01155352357Antimicrobial Effect of Hydroalcoholic Extracts of Oak Jaft (Quercus Persica) and Echium Amoenum on Shigella FlexneriMarzieh An'aam0Fatemeh Riyahi Zaniani1Farid Shirmardi Dezaki2 Department of Microbiology, Student Research Committee, Dezful University of Medical Sciences, Dezful, Iran. Department of Microbiology, Student Research Committee, Dezful University of Medical Sciences, Dezful, Iran. Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Background and Objectives: Today, because of the spread of drug resistance and the prevalence of infectious diseases, the use of medicinal plants has increased. So, in this study, the antibacterial effect of hydroalcoholic extract of Oak jaft and Echium amoenum was investigated on Shigella flexneri. Methods: In this study, hydroalcoholic extracts were extracted by maceration method and concentrated by rotary evaporator then dried immediately. Next, the antimicrobial effect of different dilutions of extracts on Shigella flexneri was investigated by disk diffusion and micro broth dilution methods and compared with two antibiotics, ciprofloxacin and trimethoprim-sulfamethoxazole. Results: The results showed that in proportion to the increase in the concentration of oak jaft extract, its antibacterial effect on Shigella flexneri also increased and 3.9 and 7.8 mg/ml of the extract were obtained by MIC and MBC dilution micro broth method, respectively. In the case of Echium amoenum extract, bacteria were grown at all dilutions (except the main stock of the extract (250 mg/ml)) and the extract had no antimicrobial effect on Shigella flexneri. Conclusion: According to the results of this study, oak jaft extract had a good inhibitory effect on Shigella flexneri and in comparison, with ciprofloxacin antibiotic, a similar inhibitory effect was observed and in comparison, with trimethoprim sulfamethoxazole, more inhibitory effect was observed.http://journal.muq.ac.ir/article-1-3142-en.htmldrug resistanceshigella flexneriplant extractsantimicrobial properties |
| spellingShingle | Marzieh An'aam Fatemeh Riyahi Zaniani Farid Shirmardi Dezaki Antimicrobial Effect of Hydroalcoholic Extracts of Oak Jaft (Quercus Persica) and Echium Amoenum on Shigella Flexneri Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum drug resistance shigella flexneri plant extracts antimicrobial properties |
| title | Antimicrobial Effect of Hydroalcoholic Extracts of Oak Jaft (Quercus Persica) and Echium Amoenum on Shigella Flexneri |
| title_full | Antimicrobial Effect of Hydroalcoholic Extracts of Oak Jaft (Quercus Persica) and Echium Amoenum on Shigella Flexneri |
| title_fullStr | Antimicrobial Effect of Hydroalcoholic Extracts of Oak Jaft (Quercus Persica) and Echium Amoenum on Shigella Flexneri |
| title_full_unstemmed | Antimicrobial Effect of Hydroalcoholic Extracts of Oak Jaft (Quercus Persica) and Echium Amoenum on Shigella Flexneri |
| title_short | Antimicrobial Effect of Hydroalcoholic Extracts of Oak Jaft (Quercus Persica) and Echium Amoenum on Shigella Flexneri |
| title_sort | antimicrobial effect of hydroalcoholic extracts of oak jaft quercus persica and echium amoenum on shigella flexneri |
| topic | drug resistance shigella flexneri plant extracts antimicrobial properties |
| url | http://journal.muq.ac.ir/article-1-3142-en.html |
| work_keys_str_mv | AT marziehanaam antimicrobialeffectofhydroalcoholicextractsofoakjaftquercuspersicaandechiumamoenumonshigellaflexneri AT fatemehriyahizaniani antimicrobialeffectofhydroalcoholicextractsofoakjaftquercuspersicaandechiumamoenumonshigellaflexneri AT faridshirmardidezaki antimicrobialeffectofhydroalcoholicextractsofoakjaftquercuspersicaandechiumamoenumonshigellaflexneri |