Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and Regeneration
Tissue engineering is a novel regenerative approach in the medicinal field that promises theregeneration of damaged tissues. Moreover, tissue engineering involves synthetic and naturalbiomaterials that facilitate tissue or organ growth outside the body. Not surprisingly, the demandfor polymer-based...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2022-05-01
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| Series: | Advanced Pharmaceutical Bulletin |
| Subjects: | |
| Online Access: | https://apb.tbzmed.ac.ir/PDF/apb-12-437.pdf |
| _version_ | 1811219285381480448 |
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| author | Varuna Naga Venkata Arjun Uppuluri Shanmugarajan Thukani Sathanantham Sai Krishna Bhimavarapu Lokesh Elumalai |
| author_facet | Varuna Naga Venkata Arjun Uppuluri Shanmugarajan Thukani Sathanantham Sai Krishna Bhimavarapu Lokesh Elumalai |
| author_sort | Varuna Naga Venkata Arjun Uppuluri |
| collection | DOAJ |
| description | Tissue engineering is a novel regenerative approach in the medicinal field that promises theregeneration of damaged tissues. Moreover, tissue engineering involves synthetic and naturalbiomaterials that facilitate tissue or organ growth outside the body. Not surprisingly, the demandfor polymer-based therapeutical approaches in skin tissue defects has increased at an effectiverate, despite the pressing clinical need. Among the 3D scaffolds for tissue engineering andregeneration approaches, hydrogel scaffolds have shown significant importance for their useas 3D cross-linked scaffolds in skin tissue regeneration due to their ideal moisture retentionproperty and porosity biocompatibility, biodegradable, and biomimetic characteristics. Inthis review, we demonstrated the choice of ideal biomaterials to fabricate the novel hydrogelscaffolds for skin tissue engineering. After a short introduction to the bioactive and drug-loadedpolymeric hydrogels, the discussion turns to fabrication and characterisation techniques of thepolymeric hydrogel scaffolds. In conclusion, we discuss the excellent wound healing potentialof stem cell-loaded hydrogels and Nano-based approaches to designing hydrogel scaffolds forskin tissue engineering. |
| first_indexed | 2024-04-12T07:23:35Z |
| format | Article |
| id | doaj.art-4e6e0334cb7245cb9985121b2e96552a |
| institution | Directory Open Access Journal |
| issn | 2228-5881 2251-7308 |
| language | English |
| last_indexed | 2024-04-12T07:23:35Z |
| publishDate | 2022-05-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Advanced Pharmaceutical Bulletin |
| spelling | doaj.art-4e6e0334cb7245cb9985121b2e96552a2022-12-22T03:42:14ZengTabriz University of Medical SciencesAdvanced Pharmaceutical Bulletin2228-58812251-73082022-05-0112343744810.34172/apb.2022.069apb-32337Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and RegenerationVaruna Naga Venkata Arjun Uppuluri0Shanmugarajan Thukani Sathanantham1Sai Krishna Bhimavarapu2Lokesh Elumalai3Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science, Technology & Advanced Studies (VISTAS), Chennai, 600 117, Tamil Nadu, India.Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science, Technology & Advanced Studies (VISTAS), Chennai, 600 117, Tamil Nadu, India.Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science, Technology & Advanced Studies (VISTAS), Chennai, 600 117, Tamil Nadu, India.Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels Institute of Science, Technology & Advanced Studies (VISTAS), Chennai, 600 117, Tamil Nadu, India.Tissue engineering is a novel regenerative approach in the medicinal field that promises theregeneration of damaged tissues. Moreover, tissue engineering involves synthetic and naturalbiomaterials that facilitate tissue or organ growth outside the body. Not surprisingly, the demandfor polymer-based therapeutical approaches in skin tissue defects has increased at an effectiverate, despite the pressing clinical need. Among the 3D scaffolds for tissue engineering andregeneration approaches, hydrogel scaffolds have shown significant importance for their useas 3D cross-linked scaffolds in skin tissue regeneration due to their ideal moisture retentionproperty and porosity biocompatibility, biodegradable, and biomimetic characteristics. Inthis review, we demonstrated the choice of ideal biomaterials to fabricate the novel hydrogelscaffolds for skin tissue engineering. After a short introduction to the bioactive and drug-loadedpolymeric hydrogels, the discussion turns to fabrication and characterisation techniques of thepolymeric hydrogel scaffolds. In conclusion, we discuss the excellent wound healing potentialof stem cell-loaded hydrogels and Nano-based approaches to designing hydrogel scaffolds forskin tissue engineering.https://apb.tbzmed.ac.ir/PDF/apb-12-437.pdfhydrogelskintissue engineeringwound healing |
| spellingShingle | Varuna Naga Venkata Arjun Uppuluri Shanmugarajan Thukani Sathanantham Sai Krishna Bhimavarapu Lokesh Elumalai Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and Regeneration Advanced Pharmaceutical Bulletin hydrogel skin tissue engineering wound healing |
| title | Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and Regeneration |
| title_full | Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and Regeneration |
| title_fullStr | Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and Regeneration |
| title_full_unstemmed | Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and Regeneration |
| title_short | Polymeric Hydrogel Scaffolds: Skin Tissue Engineering and Regeneration |
| title_sort | polymeric hydrogel scaffolds skin tissue engineering and regeneration |
| topic | hydrogel skin tissue engineering wound healing |
| url | https://apb.tbzmed.ac.ir/PDF/apb-12-437.pdf |
| work_keys_str_mv | AT varunanagavenkataarjunuppuluri polymerichydrogelscaffoldsskintissueengineeringandregeneration AT shanmugarajanthukanisathanantham polymerichydrogelscaffoldsskintissueengineeringandregeneration AT saikrishnabhimavarapu polymerichydrogelscaffoldsskintissueengineeringandregeneration AT lokeshelumalai polymerichydrogelscaffoldsskintissueengineeringandregeneration |