Opposite Pathways of Cholinergic Mechanisms of Hypoxic Preconditioning in the Hippocampus: Participation of Nicotinic α7 Receptors and Their Association with the Baseline Level of Startle Prepulse Inhibition

Opposite Pathways of Cholinergic Mechanisms of Hypoxic Preconditioning in the Hippocampus: Participation of Nicotinic α7 Receptors and Their Association with the Baseline Level of Startle Prepulse Inhibition

(1) Background. A one-time moderate hypobaric hypoxia (HBH) has a preconditioning effect whose neuronal mechanisms are not studied well. Previously, we found a stable correlation between the HBH efficiency and acoustic startle prepulse inhibition (PPI). This makes it possible to predict the individu...

Full description

Bibliographic Details
Main Authors: Elena I. Zakharova, Zinaida I. Storozheva, Andrey T. Proshin, Mikhail Yu. Monakov, Alexander M. Dudchenko
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Brain Sciences
Subjects:
adaptation to severe hypoxia
brain structures
cholinergic forebrain projections
synaptic membrane-bound choline acetyltransferase
PNU-282987
dimethyl sulfoxide
Online Access:https://www.mdpi.com/2076-3425/11/1/12

Similar Items

Similar Items