How to switch a master switch

The crystal structure of a nucleotide exchange factor in white blood cells reveals an autoinhibitory mechanism that reinforces the switch-like behaviour of the signalling protein Ras.

Bibliographic Details
Main Authors: Christopher Hein, Alfred Wittinghofer, Volker Dötsch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/01159