Functional gastrointestinal disorders are associated with capsaicin cough sensitivity in severe asthma

Functional gastrointestinal disorders are associated with capsaicin cough sensitivity in severe asthma

Background: Although sensory nerve dysfunction is related to the pathology of severe uncontrolled asthma and functional gastrointestinal disorders (FGIDs), the impact of comorbid FGIDs on the pathophysiology of severe uncontrolled asthma remains poorly understood. The aim was to clarify the physiolo...

Full description

Bibliographic Details
Main Authors:	Keima Ito, Yoshihiro Kanemitsu, Takeshi Kamiya, Kensuke Fukumitsu, Norihisa Takeda, Tomoko Tajiri, Ryota Kurokawa, Hirono Nishiyama, Jennifer Yap, Satoshi Fukuda, Takehiro Uemura, Hirotsugu Ohkubo, Ken Maeno, Yutaka Ito, Tetsuya Oguri, Masaya Takemura, Akio Niimi
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Series:	Allergology International
Subjects:	Capsaicin cough sensitivity Functional gastrointestinal disorders Sensory nerve Severe asthma Transient receptor potential vanilloid 1
Online Access:	http://www.sciencedirect.com/science/article/pii/S1323893022001137

Similar Items

Staphylococcus aureus enterotoxin sensitization is associated with declined capsaicin cough sensitivity in chronic obstructive pulmonary disease
by: Yoshihiro Kanemitsu, et al.
Published: (2024-11-01)

Decreased capsaicin cough reflex sensitivity predicts hospitalisation due to COPD
by: Yutaka Ito, et al.
Published: (2023-07-01)

Reflux-related symptoms reflect poor asthma control and the presence of airway neuronal dysfunction
by: Ryota Kurokawa, et al.
Published: (2022-07-01)

Capsaicin-fighting fire with fire
by: Poonam Agarwal, et al.
Published: (2009-01-01)

Capsaicin, Nociception and Pain
by: Bárbara Frias, et al.
Published: (2016-06-01)

A case of non-small cell lung cancer with long-term response after re-challenge with nivolumab
by: Keima Ito, et al.
Published: (2020-01-01)

Efficacy of dupilumab for airway hypersecretion and airway wall thickening in patients with moderate-to-severe asthma: A prospective, observational study
by: Tomoko Tajiri, et al.
Published: (2024-07-01)

The impact of budesonide inhalation suspension for asthma hospitalization: In terms of length of stay, recovery time from symptoms, and hospitalization costs
by: Keima Ito, et al.
Published: (2020-10-01)

The effect of intra-articular vanilloid receptor agonists on pain behavior measures in a murine model of acute monoarthritis
by: Abdullah M, et al.
Published: (2016-08-01)

TRPV1: A Target for Rational Drug Design
by: Vincenzo Carnevale, et al.
Published: (2016-08-01)

Clinical impact of gastroesophageal reflux disease in patients with subacute/chronic cough
by: Yoshihiro Kanemitsu, et al.
Published: (2019-10-01)

Diagnostic utility of fractional exhaled nitric oxide in prolonged and chronic cough according to atopic status
by: Takamitsu Asano, et al.
Published: (2017-04-01)

Productive cough associated with patient-reported outcomes and computed tomography analysis results in idiopathic pulmonary fibrosis: a single centre cross-sectional study
by: Kohei Fujita, et al.
Published: (2024-09-01)

Capsaicin alleviates the intestinal oxidative stress via activation of TRPV1/PKA/UCP2 and Keap1/Nrf2 pathways in heat-stressed mice
by: Zhihua Li, et al.
Published: (2023-09-01)

Sensitization and translocation of TRPV1 by insulin and IGF-I
by: Pauza Mary E, et al.
Published: (2005-04-01)

Molecular Surgery Concept from Bench to Bedside: A Focus on TRPV1+ Pain-Sensing Neurons
by: László Pecze, et al.
Published: (2017-06-01)

Capsaicin in Pain Management A Spicy Solution to Chronic and Neuropathic Pain
by: Konrad Pilarski, et al.
Published: (2024-07-01)

Moulds and Staphylococcus aureus enterotoxins are relevant allergens to affect Type 2 inflammation and clinical outcomes in chronic rhinosinusitis patients
by: Yoshihiro Kanemitsu, et al.
Published: (2020-11-01)

Residual Dyspnea May Predict Small Airways Dysfunction and Poor Responsiveness to Single-Inhaler Triple Therapy in Asthmatic Patients
by: Ito K, et al.
Published: (2022-11-01)

Chemical and Pharmacological Aspects of Capsaicin
by: Maria de Lourdes Reyes-Escogido, et al.
Published: (2011-01-01)

Human Lung Fibroblasts Exhibit Induced Inflammation Memory via Increased IL6 Gene Expression and Release
by: Jennifer Maries Go Yap, et al.
Published: (2022-07-01)

Serum creatinine/cystatin C ratio is a surrogate marker for sarcopenia in patients with idiopathic pulmonary fibrosis
by: Kohei Fujita, et al.
Published: (2022-05-01)

AITC inhibits fibroblast-myofibroblast transition via TRPA1-independent MAPK and NRF2/HO-1 pathways and reverses corticosteroids insensitivity in human lung fibroblasts
by: Jennifer Maries Go Yap, et al.
Published: (2021-02-01)

Genetic variation in the ATP binding cassette transporter ABCC10 is associated with neutropenia for docetaxel in Japanese lung cancer patients cohort
by: Kazuki Sone, et al.
Published: (2019-03-01)

Determination of Natural Capsaicin, Dihydrocapsaicin and Synthetic Capsaicin in Hot Pepper and Its Products by QuEChERS Combined with HPLC
by: CHENG Luyao, WEN Yajun, SHI Wenting, ZHOU Ziying, MA Liyan
Published: (2025-01-01)

Uncertainty evaluation for the determination of natural capsaicin, dihydrocapsaicin and synthetic capsaicin in edible oils and fats by LC-MS/MS
by: HUANG Hui, et al.
Published: (2022-09-01)

An autopsy case of immune-related severe colitis due to long-term use of nivolumab in a patient with non-small cell lung cancer
by: Masashi Fujikawa, et al.
Published: (2022-01-01)

Inducing Cough Reflex by Capsaicin Spray Stimulation in Patients with Acquired Brain Injury: A Preliminary Test and Proof of Concept
by: Luisa Spezzano, et al.
Published: (2023-12-01)

Capsaicin: A Two-Decade Systematic Review of Global Research Output and Recent Advances Against Human Cancer
by: Tomi Lois Adetunji, et al.
Published: (2022-07-01)

Histologic evaluation of pulpal response to MTA and capsaicin in cats
by: Zahrasadat Madani, et al.
Published: (2012-09-01)

Use of a Capsaicin Cough Challenge Test to Compare Four Different Techniques for Nebulization Delivery in Cats
by: Jesús Talavera-López, et al.
Published: (2024-07-01)

Capsaicin Nanoparticles as Therapeutic Agents against Gliomas
by: Evelin Martínez-Benavidez, et al.
Published: (2021-12-01)

Research Progress on Capsaicin: Bioactivity and Delivery Systems
by: WANG Xinyao, CHEN Mengjuan, XIAO He, LIU Yang, WANG Rongrong, JIANG Liwen
Published: (2024-02-01)

In vitro Anti-Helicobacter pylori Activity of Capsaicin
by: Isra Tayseer, et al.
Published: (2020-03-01)

Genotoxicity Evaluation of Capsaicin-Containing (CP) Pharmacopuncture, in an In Vivo Micronucleus Test
by: Ji Hye Hwang, et al.
Published: (2020-12-01)

Determination of Capsaicin and Dihydrocapsaicin in Capsicum Fruit Samples using High Performance Liquid Chromatography
by: Ayman Abdel Ghafar, et al.
Published: (2011-10-01)

PENGUJIAN EFEKTIVITAS CAPSICUM SEBAGAI SUMBER CAPSAICIN KO-ANESTESI PADA ANESTESI LOKAL
by: Aldian Mulyanto Lokaria, et al.
Published: (2015-09-01)

Capsaicin suppresses interleukin-31-induced itching partially involved in inhibiting the expression of dorsal root ganglion interleukin-31 receptor A in male mice
by: Iwao Arai, et al.
Published: (2022-01-01)

Capsaicin and carcinogenesis. Conflicting evidence regarding effects on carcinogenesis
by: Krzysztof Mariusz Halczuk, et al.
Published: (2024-02-01)

Evaluation of the Single-Dose Toxicity of Capsaicin Pharmacopuncture in Rats
by: Ji Hye Hwang, et al.
Published: (2020-08-01)