LncRNA H19 promotes the proliferation of pulmonary artery smooth muscle cells through AT1R via sponging let-7b in monocrotaline-induced pulmonary arterial hypertension

LncRNA H19 promotes the proliferation of pulmonary artery smooth muscle cells through AT1R via sponging let-7b in monocrotaline-induced pulmonary arterial hypertension

Abstract Background Pulmonary arterial hypertension (PAH) is related to inflammation, and the lncRNA H19 is associated with inflammation. However, whether PDGF-BB-H19-let-7b-AT1R axis contributes to the pathogenesis of PAH has not been thoroughly elucidated to date. This study investigated the role...

Full description

Bibliographic Details
Main Authors: Hua Su, Xiaoling Xu, Chao Yan, Yangfeng Shi, Yanjie Hu, Liangliang Dong, Songmin Ying, Kejing Ying, Ruifeng Zhang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Respiratory Research
Subjects:
LncRNA
H19
miRNA
Let-7b
Pulmonary artery hypertension
AT1R
Online Access:http://link.springer.com/article/10.1186/s12931-018-0956-z

Internet

http://link.springer.com/article/10.1186/s12931-018-0956-z

Similar Items