Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex

Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex

Legionella pneumophila is an opportunistic pathogen that causes the potentially fatal pneumonia Legionnaires’ Disease. This infection and subsequent pathology require the Dot/Icm Type IV Secretion System (T4SS) to deliver effector proteins into host cells. Compared to prototypical T4SSs, the Dot/Icm...

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Bibliographic Details
Main Authors: Clarissa L Durie, Michael J Sheedlo, Jeong Min Chung, Brenda G Byrne, Min Su, Thomas Knight, Michele Swanson, D Borden Lacy, Melanie D Ohi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
Legionella pneumophila
Type IV Secretion System
cryo-EM
pathogenesis
Online Access:https://elifesciences.org/articles/59530

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