Mutation detection and minimum inhibitory concentration determination against linezolid and clofazimine in confirmed XDR-TB clinical isolates

Mutation detection and minimum inhibitory concentration determination against linezolid and clofazimine in confirmed XDR-TB clinical isolates

Abstract Background The emergence of multidrug-resistant tuberculosis (MDR-TB) has complicated the situation due to the decline in potency of second-line anti-tubercular drugs. This limits the treatment option for extensively drug-resistant tuberculosis (XDR-TB). The aim of this study was to determi...

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Bibliographic Details
Main Authors: Kamal Singh, Swati Sharma, Tuhina Banerjee, Ankush Gupta, Shampa Anupurba
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Microbiology
Subjects:
GenoTypeMTBDRsl v.2.0 assay
REMA method
rplC gene
Rv0678 gene
Online Access:https://doi.org/10.1186/s12866-022-02622-x

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