Mycobacteria-Specific T Cells Are Generated in the Lung During Mucosal BCG Immunization or Infection With Mycobacterium tuberculosis
Specific T cell responses are central for protection against infection with M. tuberculosis. Here we show that mycobacteria-specific CD4 and CD8 T cells accumulated in the lung but not in the mediastinal lymph node (MLN) at different time points after M. tuberculosis infection or BCG immunization. P...
Main Authors: | Juan I. Basile, Ruining Liu, Wenjun Mou, Yu Gao, Berit Carow, Martin E. Rottenberg |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2020.566319/full |
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