A feedback loop between GATA2-AS1 and GATA2 promotes colorectal cancer cell proliferation, invasion, epithelial-mesenchymal transition and stemness via recruiting DDX3X

A feedback loop between GATA2-AS1 and GATA2 promotes colorectal cancer cell proliferation, invasion, epithelial-mesenchymal transition and stemness via recruiting DDX3X

Abstract Background Colorectal cancer (CRC) is a common malignant tumor with a high risk of metastasis. Long non-coding RNAs (lncRNAs) have been reported to be implicated in cancer progression via regulating its nearby gene. Herein, we investigated the function of GATA binding protein 2 (GATA2) and...

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Hlavní autoři: Yuliang Pan, Yuxing Zhu, Jun Zhang, Long Jin, Peiguo Cao
Médium: Článek
Jazyk:English
Vydáno: BMC 2022-06-01
Edice:Journal of Translational Medicine
Témata:
Colorectal cancer
GATA2-AS1
GATA2
DDX3X
On-line přístup:https://doi.org/10.1186/s12967-022-03483-8

Internet

https://doi.org/10.1186/s12967-022-03483-8

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