A feedback loop between GATA2-AS1 and GATA2 promotes colorectal cancer cell proliferation, invasion, epithelial-mesenchymal transition and stemness via recruiting DDX3X

A feedback loop between GATA2-AS1 and GATA2 promotes colorectal cancer cell proliferation, invasion, epithelial-mesenchymal transition and stemness via recruiting DDX3X

Abstract Background Colorectal cancer (CRC) is a common malignant tumor with a high risk of metastasis. Long non-coding RNAs (lncRNAs) have been reported to be implicated in cancer progression via regulating its nearby gene. Herein, we investigated the function of GATA binding protein 2 (GATA2) and...

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Autors principals:	Yuliang Pan, Yuxing Zhu, Jun Zhang, Long Jin, Peiguo Cao
Format:	Article
Idioma:	English
Publicat:	BMC 2022-06-01
Col·lecció:	Journal of Translational Medicine
Matèries:	Colorectal cancer GATA2-AS1 GATA2 DDX3X
Accés en línia:	https://doi.org/10.1186/s12967-022-03483-8

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