| Summary: | Background/Aim. Interpretation of cytological material obtained by fine
needle aspiration (FNA) of salivary glands is one of the most challenging
areas in cytopathology. FNA is performed easily, it is minimally invasive,
inexpensive, fast, reliable and provides valuable information to clinicians
about the nature of the lesion and therapeutic modalities. Ex tempore
diagnosis, frozen section (FS) is a diagnostic tool that is essential in
determining the modalities of surgical treatment of lesions of the salivary
glands. Today this method is used in determining the status of resection
margins and infiltration of adjacent anatomical structures. The aim of this
study was to present our experiences in the application of FNA and FS in the
diagnosis of salivary gland lesions and to determine the sensitivity,
specificity, predictive value, and diagnostic reliability of these methods.
Methods. The study included 36 patients. In all the patients, cytological
analysis was done before surgery and histological analysis of the surgical
material. In 23 of the patients the FS diagnostics was done. Then we compared
FNA and FS findings with histopathological findings. Results. Correlation of
cytological and histological diagnosis showed sensitivity of 83.3%,
specificity 96.67%, positive predictive value 83.3%, negative predictive
value of 96.77% and diagnostic accuracy of 97.2%. Based on the relationship
between FS diagnosis and histopathological diagnosis, the sensitivity was
100%, specificity 96.67%, while positive predictive value and diagnostic
accuracy were 100% each. Conclusion. The study confirmed that FNA is a
sensitive, reliable diagnostic method for differentiation of lesions of the
salivary glands. In cases with no posibility to definite differentiation in
FNA samples, and with the need to assess the resection margins and invasion
of anatomical structures, it is recommended to use FS diagnostics.
|
|---|