Gap junction Delta-2b (gjd2b/Cx35.1) depletion causes hyperopia and visual-motor deficiencies in the zebrafish

Gap junction Delta-2b (gjd2b/Cx35.1) depletion causes hyperopia and visual-motor deficiencies in the zebrafish

The zebrafish is a powerful model to investigate the developmental roles of electrical synapses because many signaling pathways that regulate the development of the nervous system are highly conserved from fish to humans. Here, we provide evidence linking the mammalian connexin-36 (Cx36) ortholog gj...

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Bibliographic Details
Main Authors: Cherie A. Brown-Panton, Shiva Sabour, Georg S. O. Zoidl, Christiane Zoidl, Nima Tabatabaei, Georg R. Zoidl
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
electrical synapses
zebrafish
connexin
Cx36
eye
refractive error
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1150273/full

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