Lung surfactant in subacute pulmonary disease
<p>Abstract</p> <p>Pulmonary surfactant is a surface active material composed of both lipids and proteins that is produced by alveolar type II pneumocytes. Abnormalities of surfactant in the immature lung or in the acutely inflamed mature lung are well described. However, in a vari...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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BMC
2002-04-01
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| Series: | Respiratory Research |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1186/rr168 |
| _version_ | 1828417593757663232 |
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| author | Spragg Roger G Devendra Gehan |
| author_facet | Spragg Roger G Devendra Gehan |
| author_sort | Spragg Roger G |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Pulmonary surfactant is a surface active material composed of both lipids and proteins that is produced by alveolar type II pneumocytes. Abnormalities of surfactant in the immature lung or in the acutely inflamed mature lung are well described. However, in a variety of subacute diseases of the mature lung, abnormalities of lung surfactant may also be of importance. These diseases include chronic obstructive pulmonary disease, asthma, cystic fibrosis, interstitial lung disease, pneumonia, and alveolar proteinosis. Understanding of the mechanisms that disturb the lung surfactant system may lead to novel rational therapies for these diseases.</p> |
| first_indexed | 2024-12-10T14:22:13Z |
| format | Article |
| id | doaj.art-4e91adcb9e0f4320884a4f1f8cf40d39 |
| institution | Directory Open Access Journal |
| issn | 1465-9921 |
| language | English |
| last_indexed | 2024-12-10T14:22:13Z |
| publishDate | 2002-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-4e91adcb9e0f4320884a4f1f8cf40d392022-12-22T01:45:09ZengBMCRespiratory Research1465-99212002-04-01311910.1186/rr168Lung surfactant in subacute pulmonary diseaseSpragg Roger GDevendra Gehan<p>Abstract</p> <p>Pulmonary surfactant is a surface active material composed of both lipids and proteins that is produced by alveolar type II pneumocytes. Abnormalities of surfactant in the immature lung or in the acutely inflamed mature lung are well described. However, in a variety of subacute diseases of the mature lung, abnormalities of lung surfactant may also be of importance. These diseases include chronic obstructive pulmonary disease, asthma, cystic fibrosis, interstitial lung disease, pneumonia, and alveolar proteinosis. Understanding of the mechanisms that disturb the lung surfactant system may lead to novel rational therapies for these diseases.</p>http://dx.doi.org/10.1186/rr168asthmainterstitial pulmonary fibrosispneumoniapulmonary alveolar proteinosispulmonary surfactant |
| spellingShingle | Spragg Roger G Devendra Gehan Lung surfactant in subacute pulmonary disease Respiratory Research asthma interstitial pulmonary fibrosis pneumonia pulmonary alveolar proteinosis pulmonary surfactant |
| title | Lung surfactant in subacute pulmonary disease |
| title_full | Lung surfactant in subacute pulmonary disease |
| title_fullStr | Lung surfactant in subacute pulmonary disease |
| title_full_unstemmed | Lung surfactant in subacute pulmonary disease |
| title_short | Lung surfactant in subacute pulmonary disease |
| title_sort | lung surfactant in subacute pulmonary disease |
| topic | asthma interstitial pulmonary fibrosis pneumonia pulmonary alveolar proteinosis pulmonary surfactant |
| url | http://dx.doi.org/10.1186/rr168 |
| work_keys_str_mv | AT spraggrogerg lungsurfactantinsubacutepulmonarydisease AT devendragehan lungsurfactantinsubacutepulmonarydisease |