The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment
Purpose: To determine the effectiveness of laser vitreolysis in terms of contrast sensitivity function (CSF) and vision-related quality of life (VRQol) for symptomatic floaters due to posterior vitreous detachment (PVD). Materials: This is an interventional study that involved 57 eyes of 45 patients...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=8;spage=3026;epage=3032;aulast=Goh |
| _version_ | 1811313219060367360 |
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| author | Wan Ni Goh Mushawiahti Mustapha Syed Z S Zakaria Mae-Lynn C Bastion |
| author_facet | Wan Ni Goh Mushawiahti Mustapha Syed Z S Zakaria Mae-Lynn C Bastion |
| author_sort | Wan Ni Goh |
| collection | DOAJ |
| description | Purpose: To determine the effectiveness of laser vitreolysis in terms of contrast sensitivity function (CSF) and vision-related quality of life (VRQol) for symptomatic floaters due to posterior vitreous detachment (PVD). Materials: This is an interventional study that involved 57 eyes of 45 patients with symptomatic floaters for more than 3 months. Patients underwent one to three sessions of vitreolysis via Neodymiun-doped Yttrium Aluminum Garnet (Nd:YAG) laser. We examined the CSF using the computer programs Freiburg Acuity and Contrast Test (FrACT) and VRQoL survey using the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) before, and 1 month after, vitreolysis. Results: Twelve patients had both eyes lasered and 33 patients had one eye lasered. The mean CSF improved from 3.20 ± 0.85%W to 2.64 ± 0.63%W 1 month after vitreolysis. Each use of the laser showed a significant mean difference in CSF (%W) as analyzed by paired t-test before and after the first laser (0.29 ± 0.49%W [P ≤ 0.001]); after the first and second laser (0.35 ± 0.53%W [P = 0.01]); and after second and third laser (0.21 ± 0.31%W [P = 0.02]). There was improvement in the median of four subscales in NEI VFQ-25 scores post treatment: general vision (z = −3.30, P = 0.001), near activity (z = 3.396, P = 0.001, distance activity (z = −2.788, P = 0.005), and mental health (z = −2.219, P = 0.026). The mean scores increased to 79.55 ± 9.45 from the baseline 75.06 ± 9.69 (P ≤ 0.001). No adverse events were recorded 1 month after the laser treatments. Conclusion: Vitreolysis by Nd:YAG laser improved the CFS and VRQoL in symptomatic PVD patients. |
| first_indexed | 2024-04-13T10:49:59Z |
| format | Article |
| id | doaj.art-4e92665fee64432f97ebf31137f26494 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-13T10:49:59Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-4e92665fee64432f97ebf31137f264942022-12-22T02:49:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-017083026303210.4103/ijo.IJO_3198_21The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachmentWan Ni GohMushawiahti MustaphaSyed Z S ZakariaMae-Lynn C BastionPurpose: To determine the effectiveness of laser vitreolysis in terms of contrast sensitivity function (CSF) and vision-related quality of life (VRQol) for symptomatic floaters due to posterior vitreous detachment (PVD). Materials: This is an interventional study that involved 57 eyes of 45 patients with symptomatic floaters for more than 3 months. Patients underwent one to three sessions of vitreolysis via Neodymiun-doped Yttrium Aluminum Garnet (Nd:YAG) laser. We examined the CSF using the computer programs Freiburg Acuity and Contrast Test (FrACT) and VRQoL survey using the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) before, and 1 month after, vitreolysis. Results: Twelve patients had both eyes lasered and 33 patients had one eye lasered. The mean CSF improved from 3.20 ± 0.85%W to 2.64 ± 0.63%W 1 month after vitreolysis. Each use of the laser showed a significant mean difference in CSF (%W) as analyzed by paired t-test before and after the first laser (0.29 ± 0.49%W [P ≤ 0.001]); after the first and second laser (0.35 ± 0.53%W [P = 0.01]); and after second and third laser (0.21 ± 0.31%W [P = 0.02]). There was improvement in the median of four subscales in NEI VFQ-25 scores post treatment: general vision (z = −3.30, P = 0.001), near activity (z = 3.396, P = 0.001, distance activity (z = −2.788, P = 0.005), and mental health (z = −2.219, P = 0.026). The mean scores increased to 79.55 ± 9.45 from the baseline 75.06 ± 9.69 (P ≤ 0.001). No adverse events were recorded 1 month after the laser treatments. Conclusion: Vitreolysis by Nd:YAG laser improved the CFS and VRQoL in symptomatic PVD patients.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=8;spage=3026;epage=3032;aulast=Gohcontrast sensitivity functionfloaterslaser vitreolysisneodymiun-doped yttrium aluminum garnet laserposterior vitreous detachment |
| spellingShingle | Wan Ni Goh Mushawiahti Mustapha Syed Z S Zakaria Mae-Lynn C Bastion The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment Indian Journal of Ophthalmology contrast sensitivity function floaters laser vitreolysis neodymiun-doped yttrium aluminum garnet laser posterior vitreous detachment |
| title | The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment |
| title_full | The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment |
| title_fullStr | The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment |
| title_full_unstemmed | The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment |
| title_short | The effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment |
| title_sort | effectiveness of laser vitreolysis for vitreous floaters in posterior vitreous detachment |
| topic | contrast sensitivity function floaters laser vitreolysis neodymiun-doped yttrium aluminum garnet laser posterior vitreous detachment |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=8;spage=3026;epage=3032;aulast=Goh |
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