KITENIN promotes aerobic glycolysis through PKM2 induction by upregulating the c-Myc/hnRNPs axis in colorectal cancer

Abstract Purpose The oncoprotein KAI1 C-terminal interacting tetraspanin (KITENIN; vang-like 1) promotes cell metastasis, invasion, and angiogenesis, resulting in shorter survival times in cancer patients. Here, we aimed to determine the effects of KITENIN on the energy metabolism of human colorecta...

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Bibliographic Details
Main Authors: Mücahit Varlı, Sung Jin Kim, Myung-Giun Noh, Yoon Gyoon Kim, Hyung-Ho Ha, Kyung Keun Kim, Hangun Kim
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-023-01089-1