Using a Network-Based Analysis Approach to Investigate the Involvement of <i>S. aureus</i> in the Pathogenesis of Granulomatosis with Polyangiitis

Using a Network-Based Analysis Approach to Investigate the Involvement of <i>S. aureus</i> in the Pathogenesis of Granulomatosis with Polyangiitis

Chronic nasal carriage of <i>Staphylococcus aureus</i> (SA) has been shown to be significantly higher in GPA patients when compared to healthy subjects, as well as being associated with increased endonasal activity and disease relapse. The aim of this study was to investigate SA involvem...

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Bibliographic Details
Main Authors: Gregory Rowland, Andreas Kronbichler, Rona Smith, David Jayne, Piet H. van der Graaf, Vijayalakshmi Chelliah
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
granulomatosis with polyangiitis
ANCA associated vasculitis
<i>Staphylococcus aureus</i>
network-based analysis
disease network
molecular signatures
Online Access:https://www.mdpi.com/1422-0067/24/3/1822

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