Unilateral Hypofunction of the Masseter Leads to Molecular and 3D Morphometric Signs of Atrophy in Ipsilateral Agonist Masticatory Muscles in Adult Mice

Unilateral Hypofunction of the Masseter Leads to Molecular and 3D Morphometric Signs of Atrophy in Ipsilateral Agonist Masticatory Muscles in Adult Mice

Mice are commonly used to study mandibular dynamics due to their similarity in chewing cycle patterns with humans. Adult mice treated unilaterally with botulinum toxin type A (BoNTA) in the masseter exhibit atrophy of this muscle characterized by an increase in the gene expression of atrophy-related...

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Bibliographic Details
Main Authors: Julián Balanta-Melo, Andrea Eyquem-Reyes, Noelia Blanco, Walter Vásquez, Kornelius Kupczik, Viviana Toro-Ibacache, Sonja Buvinic
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
masticatory muscles
X-ray microtomography
muscular atrophy
botulinum toxins
type A
Online Access:https://www.mdpi.com/1422-0067/24/19/14740

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