Down-Regulation of Protein Kinase C-ε by Prolonged Incubation with PMA Inhibits the Proliferation of Vascular Smooth Muscle Cells

Down-Regulation of Protein Kinase C-ε by Prolonged Incubation with PMA Inhibits the Proliferation of Vascular Smooth Muscle Cells

Background/Aims: Phorbol myristate acetate (PMA) exerts a pleiotropic effect on the growth and differentiation of various cells. Protein kinase Cs (PKCs) plays a central role in mediating the effects of PMA on cells. The present study investigated whether the down-regulation of protein kinase C-ε (P...

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Bibliographic Details
Main Authors: Huixuan Zhou, Yan Wang, Quanhong Zhou, Bin Wu, Aizhong Wang, Wei Jiang, Li Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Protein Kinase C-ε
Phorbol myristate acetate (PMA)
Proliferation
Vascular Smooth Muscle Cell (VSMC)
Online Access:http://www.karger.com/Article/FullText/452553

Internet

http://www.karger.com/Article/FullText/452553

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