A digital health home intervention for people within the Alzheimer’s disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial
AbstractPurpose This study tested the efficacy of digital-health home intervention for people within the Alzheimer’s disease (AD)-continuum.Methods Thirty people within the AD continuum were randomly assigned to a telerehabilitation (ABILITY; 6 males, Mage=78.2 ± 3.95) or treatment as usual (TAU; 8...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2023.2185672 |
| _version_ | 1827380531210223616 |
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| author | Federica Rossetto Sara Isernia Olivia Realdon Francesca Borgnis Valeria Blasi Chiara Pagliari Monia Cabinio Margherita Alberoni Fabrizia Mantovani Mario Clerici Francesca Baglio |
| author_facet | Federica Rossetto Sara Isernia Olivia Realdon Francesca Borgnis Valeria Blasi Chiara Pagliari Monia Cabinio Margherita Alberoni Fabrizia Mantovani Mario Clerici Francesca Baglio |
| author_sort | Federica Rossetto |
| collection | DOAJ |
| description | AbstractPurpose This study tested the efficacy of digital-health home intervention for people within the Alzheimer’s disease (AD)-continuum.Methods Thirty people within the AD continuum were randomly assigned to a telerehabilitation (ABILITY; 6 males, Mage=78.2 ± 3.95) or treatment as usual (TAU; 8 males, Mage=77.13 ± 6.38), performing cognitive and physical activities at home for six weeks. The ABILITY intervention additionally included a digital platform enabling communication between the hospital and the patient’s home. Efficiency, such as adherence, perceived fit of demands and skills, usability, and effectiveness measures, including neuropsychological level, neuropsychiatric symptoms, and autonomy in daily living, were collected before (T0), after the treatment (T1), and at the 1-year-follow-up (T2).Results The ABILITY program was efficient, with a higher adherence (81% vs. 62%), a higher perceived fit of demands and skills than TAU (p<.05), and a good level of technology usability. In terms of effectiveness, a treatment effect (ABILITY > TAU) emerged on the global cognitive level, especially in language, executive functions, and memory domains. Moreover, a treatment carry-over effect (1-year follow-up) was observed in global cognitive functions (especially language) (ABILITY > TAU), behavioral symptoms, and caregiver distress (TAU > ABILITY).Conclusions Our preliminary findings suggest that ABILITY is a promising eHealth intervention to improve at-home treatment adherence and to preserve cognitive and behavioral abilities. |
| first_indexed | 2024-03-08T13:35:17Z |
| format | Article |
| id | doaj.art-4e9dc67b1f624764b3310219095aa83a |
| institution | Directory Open Access Journal |
| issn | 0785-3890 1365-2060 |
| language | English |
| last_indexed | 2024-03-08T13:35:17Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj.art-4e9dc67b1f624764b3310219095aa83a2024-01-16T19:13:21ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602023-12-015511080109110.1080/07853890.2023.2185672A digital health home intervention for people within the Alzheimer’s disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trialFederica Rossetto0Sara Isernia1Olivia Realdon2Francesca Borgnis3Valeria Blasi4Chiara Pagliari5Monia Cabinio6Margherita Alberoni7Fabrizia Mantovani8Mario Clerici9Francesca Baglio10IRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyDepartment of Human Sciences for Education, Università degli Studi di Milano-Bicocca, Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyDepartment of Human Sciences for Education, Università degli Studi di Milano-Bicocca, Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, ItalyAbstractPurpose This study tested the efficacy of digital-health home intervention for people within the Alzheimer’s disease (AD)-continuum.Methods Thirty people within the AD continuum were randomly assigned to a telerehabilitation (ABILITY; 6 males, Mage=78.2 ± 3.95) or treatment as usual (TAU; 8 males, Mage=77.13 ± 6.38), performing cognitive and physical activities at home for six weeks. The ABILITY intervention additionally included a digital platform enabling communication between the hospital and the patient’s home. Efficiency, such as adherence, perceived fit of demands and skills, usability, and effectiveness measures, including neuropsychological level, neuropsychiatric symptoms, and autonomy in daily living, were collected before (T0), after the treatment (T1), and at the 1-year-follow-up (T2).Results The ABILITY program was efficient, with a higher adherence (81% vs. 62%), a higher perceived fit of demands and skills than TAU (p<.05), and a good level of technology usability. In terms of effectiveness, a treatment effect (ABILITY > TAU) emerged on the global cognitive level, especially in language, executive functions, and memory domains. Moreover, a treatment carry-over effect (1-year follow-up) was observed in global cognitive functions (especially language) (ABILITY > TAU), behavioral symptoms, and caregiver distress (TAU > ABILITY).Conclusions Our preliminary findings suggest that ABILITY is a promising eHealth intervention to improve at-home treatment adherence and to preserve cognitive and behavioral abilities.https://www.tandfonline.com/doi/10.1080/07853890.2023.2185672TelerehabilitationAlzheimer’s diseaseMild Cognitive ImpairmentRehabilitationDisabilityDementia |
| spellingShingle | Federica Rossetto Sara Isernia Olivia Realdon Francesca Borgnis Valeria Blasi Chiara Pagliari Monia Cabinio Margherita Alberoni Fabrizia Mantovani Mario Clerici Francesca Baglio A digital health home intervention for people within the Alzheimer’s disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial Annals of Medicine Telerehabilitation Alzheimer’s disease Mild Cognitive Impairment Rehabilitation Disability Dementia |
| title | A digital health home intervention for people within the Alzheimer’s disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial |
| title_full | A digital health home intervention for people within the Alzheimer’s disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial |
| title_fullStr | A digital health home intervention for people within the Alzheimer’s disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial |
| title_full_unstemmed | A digital health home intervention for people within the Alzheimer’s disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial |
| title_short | A digital health home intervention for people within the Alzheimer’s disease continuum: results from the Ability-TelerehABILITation pilot randomized controlled trial |
| title_sort | digital health home intervention for people within the alzheimer s disease continuum results from the ability telerehabilitation pilot randomized controlled trial |
| topic | Telerehabilitation Alzheimer’s disease Mild Cognitive Impairment Rehabilitation Disability Dementia |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2023.2185672 |
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