The malignancy suppression and ferroptosis facilitation of BCL6 in gastric cancer mediated by FZD7 repression are strengthened by RNF180/RhoC pathway

The malignancy suppression and ferroptosis facilitation of BCL6 in gastric cancer mediated by FZD7 repression are strengthened by RNF180/RhoC pathway

Abstract Background B-cell lymphoma 6 (BCL6) is a transcription repressor that plays a tumor suppressor or promoting role in various tumors. However, its function and molecular mechanism in gastric cancer (GC) remain unclear. Ferroptosis, a novel programmed cell death, is closely related to tumor de...

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Bibliographic Details
Main Authors: Shiwei Guo, Jingyu Deng, Pengliang Wang, Fan Kou, Zizhen Wu, Nannan Zhang, Zhenzhen Zhao, Yongzhan Nie, Lili Yang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Cell & Bioscience
Subjects:
BCL6
Gastric cancer
Proliferation
Metastasis
FZD7
Wnt/β-catenin pathway
Online Access:https://doi.org/10.1186/s13578-023-01020-8

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