Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations
Polycystic ovary syndrome (PCOS) is one of the most common heterogeneous conditions of the endocrine reproductive system in women of childbearing age. Hyperandrogenism and oligomenorrhea are the two core characteristics of PCOS, a complicated and multifaceted illness. The condition is also linked to...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
|
| Series: | Life |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-1729/12/12/1974 |
| _version_ | 1827638100538425344 |
|---|---|
| author | Afrin Yasmin Shubhadeep Roychoudhury Arun Paul Choudhury A. B. Fuzayel Ahmed Sulagna Dutta Filomena Mottola Vivek Verma Jogen C. Kalita Dhruv Kumar Pallav Sengupta Adriana Kolesarova |
| author_facet | Afrin Yasmin Shubhadeep Roychoudhury Arun Paul Choudhury A. B. Fuzayel Ahmed Sulagna Dutta Filomena Mottola Vivek Verma Jogen C. Kalita Dhruv Kumar Pallav Sengupta Adriana Kolesarova |
| author_sort | Afrin Yasmin |
| collection | DOAJ |
| description | Polycystic ovary syndrome (PCOS) is one of the most common heterogeneous conditions of the endocrine reproductive system in women of childbearing age. Hyperandrogenism and oligomenorrhea are the two core characteristics of PCOS, a complicated and multifaceted illness. The condition is also linked to several major side effects, which include type 2 diabetes, early atherosclerosis, infertility, and endometrial cancer. There are few facts and statistics available on PCOS prevalence internationally due to the significant degree of geographic and ethnic variance and inconsistency caused by different diagnosis standards. Limited (<i>n</i> = 179) explorations have been made in the context of the prevalence of this complicated illness so far, and out of these, only 55 studies have discussed its association with race and/or ethnicity. However, those studies remain restricted due to the small sample size, biased selection, and the lack of comparative studies. Variations in PCOS prevalence frequency also arise due to different diagnostic criteria, as well as racial and ethnic differences, associated lifestyle factors, and subsequent illnesses that affect the accuracy of the diagnosis. The main objective behind this systematic review is to provide comprehensive epidemiological data on PCOS that is organized geographically. This evidence-based study also provides an overview of the clinical management of PCOS to instigate further research on this complex endocrinological condition and the subsequent development of preventive treatment strategies. |
| first_indexed | 2024-03-09T16:10:52Z |
| format | Article |
| id | doaj.art-4ea17436bdee4e5e8da2d6f72d9cce32 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T16:10:52Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-4ea17436bdee4e5e8da2d6f72d9cce322023-11-24T16:11:24ZengMDPI AGLife2075-17292022-11-011212197410.3390/life12121974Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic VariationsAfrin Yasmin0Shubhadeep Roychoudhury1Arun Paul Choudhury2A. B. Fuzayel Ahmed3Sulagna Dutta4Filomena Mottola5Vivek Verma6Jogen C. Kalita7Dhruv Kumar8Pallav Sengupta9Adriana Kolesarova10Department of Life Science and Bioinformatics, Assam University, Silchar 788011, IndiaDepartment of Life Science and Bioinformatics, Assam University, Silchar 788011, IndiaDepartment of Obstetrics and Gynecology, Silchar Medical College and Hospital, Silchar 788014, IndiaDepartment of Obstetrics and Gynecology, Silchar Medical College and Hospital, Silchar 788014, IndiaSchool of Medical Sciences, Bharath Institute of Higher Education and Research (BIHER), Chennai 600126, IndiaDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania Luigi Vanvitelli, 81100 Caserta, ItalyDepartment of Statistics, Assam University, Silchar 788011, IndiaDepartment of Zoology, Gauhati University, Guwahati 781014, IndiaSchool of Health Sciences and Technology, UPES University, Dehradun 248007, IndiaPhysiology Unit, Department of Biomedical Sciences, College of Medicine, Gulf Medical University, Ajman 4184, United Arab EmiratesFaculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, 94901 Nitra, SlovakiaPolycystic ovary syndrome (PCOS) is one of the most common heterogeneous conditions of the endocrine reproductive system in women of childbearing age. Hyperandrogenism and oligomenorrhea are the two core characteristics of PCOS, a complicated and multifaceted illness. The condition is also linked to several major side effects, which include type 2 diabetes, early atherosclerosis, infertility, and endometrial cancer. There are few facts and statistics available on PCOS prevalence internationally due to the significant degree of geographic and ethnic variance and inconsistency caused by different diagnosis standards. Limited (<i>n</i> = 179) explorations have been made in the context of the prevalence of this complicated illness so far, and out of these, only 55 studies have discussed its association with race and/or ethnicity. However, those studies remain restricted due to the small sample size, biased selection, and the lack of comparative studies. Variations in PCOS prevalence frequency also arise due to different diagnostic criteria, as well as racial and ethnic differences, associated lifestyle factors, and subsequent illnesses that affect the accuracy of the diagnosis. The main objective behind this systematic review is to provide comprehensive epidemiological data on PCOS that is organized geographically. This evidence-based study also provides an overview of the clinical management of PCOS to instigate further research on this complex endocrinological condition and the subsequent development of preventive treatment strategies.https://www.mdpi.com/2075-1729/12/12/1974polycystic ovaryPCOSprevalencediagnostic criteriahyperandrogenismhirsutism |
| spellingShingle | Afrin Yasmin Shubhadeep Roychoudhury Arun Paul Choudhury A. B. Fuzayel Ahmed Sulagna Dutta Filomena Mottola Vivek Verma Jogen C. Kalita Dhruv Kumar Pallav Sengupta Adriana Kolesarova Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations Life polycystic ovary PCOS prevalence diagnostic criteria hyperandrogenism hirsutism |
| title | Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations |
| title_full | Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations |
| title_fullStr | Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations |
| title_full_unstemmed | Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations |
| title_short | Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations |
| title_sort | polycystic ovary syndrome an updated overview foregrounding impacts of ethnicities and geographic variations |
| topic | polycystic ovary PCOS prevalence diagnostic criteria hyperandrogenism hirsutism |
| url | https://www.mdpi.com/2075-1729/12/12/1974 |
| work_keys_str_mv | AT afrinyasmin polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT shubhadeeproychoudhury polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT arunpaulchoudhury polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT abfuzayelahmed polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT sulagnadutta polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT filomenamottola polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT vivekverma polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT jogenckalita polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT dhruvkumar polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT pallavsengupta polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations AT adrianakolesarova polycysticovarysyndromeanupdatedoverviewforegroundingimpactsofethnicitiesandgeographicvariations |