A systematic analysis of gene–gene interaction in multiple sclerosis

A systematic analysis of gene–gene interaction in multiple sclerosis

Abstract Background For the most part, genome-wide association studies (GWAS) have only partially explained the heritability of complex diseases. One of their limitations is to assume independent contributions of individual variants to the phenotype. Many tools have therefore been developed to inves...

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Bibliographic Details
Main Authors: Lotfi Slim, Clément Chatelain, Hélène de Foucauld, Chloé-Agathe Azencott
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Medical Genomics
Subjects:
GWAS
Epistasis
Multiple sclerosis
Gene–gene interaction
Causal inference
Online Access:https://doi.org/10.1186/s12920-022-01247-3

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