Potential role of Lu/BCAM in HIV-related atherosclerosis
Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules....
| Główni autorzy: | , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
AOSIS
2019-09-01
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| Seria: | African Journal of Laboratory Medicine |
| Hasła przedmiotowe: | |
| Dostęp online: | https://ajlmonline.org/index.php/ajlm/article/view/792 |
| Streszczenie: | Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients. |
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| ISSN: | 2225-2002 2225-2010 |