Potential role of Lu/BCAM in HIV-related atherosclerosis
Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules....
| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
AOSIS
2019-09-01
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| coleção: | African Journal of Laboratory Medicine |
| Assuntos: | |
| Acesso em linha: | https://ajlmonline.org/index.php/ajlm/article/view/792 |
| Resumo: | Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients. |
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| ISSN: | 2225-2002 2225-2010 |