Sensitivity to sequencing depth in single-cell cancer genomics

Abstract Background Querying cancer genomes at single-cell resolution is expected to provide a powerful framework to understand in detail the dynamics of cancer evolution. However, given the high costs currently associated with single-cell sequencing, together with the inevitable technical noise ari...

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Autori principali: João M. Alves, David Posada
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2018-04-01
Serie:Genome Medicine
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Accesso online:http://link.springer.com/article/10.1186/s13073-018-0537-2