Sensitivity to sequencing depth in single-cell cancer genomics
Abstract Background Querying cancer genomes at single-cell resolution is expected to provide a powerful framework to understand in detail the dynamics of cancer evolution. However, given the high costs currently associated with single-cell sequencing, together with the inevitable technical noise ari...
Main Authors: | João M. Alves, David Posada |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
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Series: | Genome Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13073-018-0537-2 |
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