Sensitivity to sequencing depth in single-cell cancer genomics

Abstract Background Querying cancer genomes at single-cell resolution is expected to provide a powerful framework to understand in detail the dynamics of cancer evolution. However, given the high costs currently associated with single-cell sequencing, together with the inevitable technical noise ari...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: João M. Alves, David Posada
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2018-04-01
Σειρά:Genome Medicine
Θέματα:
Διαθέσιμο Online:http://link.springer.com/article/10.1186/s13073-018-0537-2