Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis

Silent thyroiditis is a rare cause of thyrotoxic periodic paralysis. The objective was to present a case of silent thyroiditis presenting as periodic paralysis. A 23-year-old man presented with recurrent acute flaccid predominantly proximal weakness of all four limbs. He had a similar episode 3 week...

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Main Authors: Debmalya Sanyal, Shakya Bhattacharjee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=2;spage=218;epage=220;aulast=Sanyal
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author Debmalya Sanyal
Shakya Bhattacharjee
author_facet Debmalya Sanyal
Shakya Bhattacharjee
author_sort Debmalya Sanyal
collection DOAJ
description Silent thyroiditis is a rare cause of thyrotoxic periodic paralysis. The objective was to present a case of silent thyroiditis presenting as periodic paralysis. A 23-year-old man presented with recurrent acute flaccid predominantly proximal weakness of all four limbs. He had a similar episode 3 weeks back. On examination he was found to have hypokalemia secondary to thyrotoxicosis. Clinically there were no features of thyrotoxicosis or thyroiditis. He was initially treated with intravenous and later oral potassium supplementation and propranolol. At 8 weeks of follow-up his thyroid profile became normal and his propranolol was stopped. He had no further recurrence of paralysis. He was diagnosed as a case silent thyroiditis presenting as thyrotoxic periodic paralysis. In cases of recurrent or acute flaccid muscle paralysis, it is important to suspect thyrotoxicosis, even if asymptomatic. Definitive treatment of thyrotoxicosis prevents recurrence.
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spelling doaj.art-4eac876ebd354fd0b54e20e50e5b7d092022-12-22T01:06:44ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492013-01-0116221822010.4103/0972-2327.112471Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditisDebmalya SanyalShakya BhattacharjeeSilent thyroiditis is a rare cause of thyrotoxic periodic paralysis. The objective was to present a case of silent thyroiditis presenting as periodic paralysis. A 23-year-old man presented with recurrent acute flaccid predominantly proximal weakness of all four limbs. He had a similar episode 3 weeks back. On examination he was found to have hypokalemia secondary to thyrotoxicosis. Clinically there were no features of thyrotoxicosis or thyroiditis. He was initially treated with intravenous and later oral potassium supplementation and propranolol. At 8 weeks of follow-up his thyroid profile became normal and his propranolol was stopped. He had no further recurrence of paralysis. He was diagnosed as a case silent thyroiditis presenting as thyrotoxic periodic paralysis. In cases of recurrent or acute flaccid muscle paralysis, it is important to suspect thyrotoxicosis, even if asymptomatic. Definitive treatment of thyrotoxicosis prevents recurrence.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=2;spage=218;epage=220;aulast=SanyalHypokalemiaoral potassiumperiodic paralysisthyroiditisthyrotoxicosis
spellingShingle Debmalya Sanyal
Shakya Bhattacharjee
Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis
Annals of Indian Academy of Neurology
Hypokalemia
oral potassium
periodic paralysis
thyroiditis
thyrotoxicosis
title Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis
title_full Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis
title_fullStr Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis
title_full_unstemmed Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis
title_short Thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis
title_sort thyrotoxic hypokalemic periodic paralysis as the presenting symptom of silent thyroiditis
topic Hypokalemia
oral potassium
periodic paralysis
thyroiditis
thyrotoxicosis
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=2;spage=218;epage=220;aulast=Sanyal
work_keys_str_mv AT debmalyasanyal thyrotoxichypokalemicperiodicparalysisasthepresentingsymptomofsilentthyroiditis
AT shakyabhattacharjee thyrotoxichypokalemicperiodicparalysisasthepresentingsymptomofsilentthyroiditis