Conserved mechanisms of self-renewal and pluripotency in mouse and human ESCs regulated by simulated microgravity using a 3D clinostat

Conserved mechanisms of self-renewal and pluripotency in mouse and human ESCs regulated by simulated microgravity using a 3D clinostat

Abstract Embryonic stem cells (ESCs) exhibit unique attributes of boundless self-renewal and pluripotency, making them invaluable for fundamental investigations and clinical endeavors. Previous examinations of microgravity effects on ESC self-renewal and differentiation have predominantly maintained...

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Bibliographic Details
Main Authors: Ying Ye, Wenyan Xie, Zhaoru Ma, Xuepeng Wang, Yi Wen, Xuemei Li, Hongqian Qi, Hao Wu, Jinnan An, Yan Jiang, Xinyi Lu, Guokai Chen, Shijun Hu, Elizabeth A. Blaber, Xi Chen, Lei Chang, Wensheng Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01846-2

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