Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis

Subarachnoid hemorrhage (SAH) is an uncommon complication of systemic lupus erythematosus (SLE). Solitary association of fatal spinal SAH as a complication of SLE, has not been encountered much in literature although coexisting acute cerebral and spinal SAH have been associated with SLE. We present...

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Main Authors: Xiang Yang, Seidu A. Richard, Jiagang Liu, Siqing Huang
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Clinics and Practice
Subjects:
Online Access:https://www.clinicsandpractice.org/index.php/cp/article/view/1069
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author Xiang Yang
Seidu A. Richard
Jiagang Liu
Siqing Huang
author_facet Xiang Yang
Seidu A. Richard
Jiagang Liu
Siqing Huang
author_sort Xiang Yang
collection DOAJ
description Subarachnoid hemorrhage (SAH) is an uncommon complication of systemic lupus erythematosus (SLE). Solitary association of fatal spinal SAH as a complication of SLE, has not been encountered much in literature although coexisting acute cerebral and spinal SAH have been associated with SLE. We present a 39-year old female with initial diagnosis of SLE eight years ago who suddenly developed a productive cough, acute abdomen and paralysis of the lower limbs. Magnetic resonance imaging of the spine revealed thoracic spinal SAH with varying degrees of thoracic spinal cord compression. The hemorrhage was total evacuated via surgery. She regained normal function of her lower limbers after the operation with no further neurological complications. One of the rare but fatal complications of SLE is solitary spinal SAH without cranial involvement. The best and most appropriate management of this kind of presentation is surgical decompression of the hematoma with total hemostasis. The cause of hemorrhage should be identified intra-operatively and treated appropriately.
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spelling doaj.art-4eb210294a16456ba08d4cfaa3cfe7b82022-12-22T04:28:36ZengMDPI AGClinics and Practice2039-72752039-72832018-05-018210.4081/cp.2018.1069Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysisXiang Yang0Seidu A. Richard1Jiagang Liu2Siqing Huang3Department of Neurosurgery, West China Hospital, Sichuan UniversityDepartment of Neurosurgery, West China Hospital, Sichuan University, P.R China; Department of Immunology, Jiangsu University, Jiangsu, P.R. China; Department of Surgery, Volta Regional Hospital, Ho, GhanaDepartment of Neurosurgery, West China Hospital, Sichuan UniversityDepartment of Neurosurgery, West China Hospital, Sichuan UniversitySubarachnoid hemorrhage (SAH) is an uncommon complication of systemic lupus erythematosus (SLE). Solitary association of fatal spinal SAH as a complication of SLE, has not been encountered much in literature although coexisting acute cerebral and spinal SAH have been associated with SLE. We present a 39-year old female with initial diagnosis of SLE eight years ago who suddenly developed a productive cough, acute abdomen and paralysis of the lower limbs. Magnetic resonance imaging of the spine revealed thoracic spinal SAH with varying degrees of thoracic spinal cord compression. The hemorrhage was total evacuated via surgery. She regained normal function of her lower limbers after the operation with no further neurological complications. One of the rare but fatal complications of SLE is solitary spinal SAH without cranial involvement. The best and most appropriate management of this kind of presentation is surgical decompression of the hematoma with total hemostasis. The cause of hemorrhage should be identified intra-operatively and treated appropriately.https://www.clinicsandpractice.org/index.php/cp/article/view/1069Subarachnoid hemorrhagesystemic lupus erythematosusflare upspinalparalysis.
spellingShingle Xiang Yang
Seidu A. Richard
Jiagang Liu
Siqing Huang
Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis
Clinics and Practice
Subarachnoid hemorrhage
systemic lupus erythematosus
flare up
spinal
paralysis.
title Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis
title_full Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis
title_fullStr Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis
title_full_unstemmed Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis
title_short Systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis
title_sort systemic lupus erythematosus flare up as acute spinal subarachnoid hemorrhage with bilateral lower limb paralysis
topic Subarachnoid hemorrhage
systemic lupus erythematosus
flare up
spinal
paralysis.
url https://www.clinicsandpractice.org/index.php/cp/article/view/1069
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