B4galnt2-mediated host glycosylation influences the susceptibility to Citrobacter rodentium infection

B4galnt2-mediated host glycosylation influences the susceptibility to Citrobacter rodentium infection

Histo-blood group antigens in the intestinal mucosa play important roles in host–microbe interactions and modulate the susceptibility to enteric pathogens. The B4galnt2 gene, expressed in the GI tract of most mammals, including humans, encodes a beta-1,4-N-acetylgalactosaminyltransferase enzyme whic...

Full description

Bibliographic Details
Main Authors: Abdulhadi Suwandi, Kris Gerard Alvarez, Alibek Galeev, Natalie Steck, Christian U. Riedel, José Luis Puente, John F. Baines, Guntram A. Grassl
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
B4galnt2
Citrobacter
intestinal inflammation
intestinal glycans
infectious colitis
gut colonization
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.980495/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.980495/full

Similar Items